Pulmonary & Nasal Drug Delivery
Issue No #53
December 16th, 2014
Inside the magazine
EXPERTISE IN DEVELOPMENT, MANUFACTURING & COMMERCIALISATION
3M Drug Delivery Systems reports on how it has achieved significant successes thanks to its deep expertise in the field of MDIs.
Specialty Coating Systems
PROTECTING INHALATION DRUG DELIVERY DEVICES WITH PARYLENE CONFORMAL COATINGS
Dick Molin describes applications of Parylene coatings as protective barrier coatings in inhalable drug delivery devices, and the detailed characteristics of Parylene which make it particularly suited to these applications.
Dr Laurent Vecellio
SONIC NEBULISATION IN RHINOLOGY
Laurent Vecellio, Sandrine Le Guellec and Gilles Chantrel describe a sonic nasal nebuliser that operates with an acoustic frequency of 100Hz, and clinical studies demonstrating its efficacy in the delivery of treatments for CRS.
Dr Carole Evans
QUALITY BY DESIGN IN INHALATION PRODUCT DEVELOPMENT
Carole Evans and Lei Mao explore the application and principles of quality by design in the development, manufacture and commercialisation of inhaled pharmaceutical products.
Dr Eunice Costa
DESIGN OF COMPOSITE PARTICLES VIA SPRAY DRYING FOR DPI FORMULATIONS
Eunice Costa, Filipe Neves and Cláudia Moura describe how composite formulations - API embedded in an excipient matrix - overcome the challenges in inhalation powder development.
Dr Joel Bell
EFFECTS OF STATIC ON PLASTICS USED IN DRUG DELIVERY DEVICES
Drug delivery in dry-powder and aerosol inhalers can be hindered by static attraction of the drug substance to plastics used in the drug flow path. JoelBell and Josh Blackmore report a series of projects to characterise this interaction.
Prof David Price
THE SIGNIFICANCE OF INHALER TECHNIQUE & HOW TO IMPROVE IT
Professor David Price describes a significant and long-standing unmet need for inhaler technique to be improved in patients with asthma and COPD, and sets forth strategies to achieve the sorely needed improvements.
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