WEARABLES

WEARABLES

Victoria Morgan

West Pharmaceutical Services

HOW LARGE-VOLUME WEARABLES REVOLUTIONISE THE PATIENT EXPERIENCE

Victoria Morgan looks at how the combination of large-volume medicines and the trend for wearable devices is transforming life for patients, highlighting the company's new-generation SmartDose 10 mL platform.

EXPERT VIEW

Michael Penman

THE CHALLENGES OF VERIFYING A WEARABLE INFUSOR

Michael Penman shows why it is important to verify body-worn infusor performance, highlighting the challenges and learnings from an example where Team Consulting was tasked with the design and verification of one such wearable device.

EXPERT VIEW

Cory Costantino

A QUICK GUIDE TO USABILITY FOR WEARABLE INJECTORS

Cory Costantino and Lauren Fennelly list some typical steps a user might take while using wearable injectors, providing tips and points to note at each step, including design tips that might pre-empt potential interaction problems, and points to consider when conducting usability testing.

CONFERENCE SHOWCASE

Dr Falk Klar

PDA

2019 PDA UNIVERSE OF PRE-FILLED SYRINGES AND INJECTION DEVICES PREVIEW

PDA Europe presents the 16th edition of its signature event Universe of Pre-filled Syringes & Injection Devices – an important conference for people working in the fields of parenteral drug, and device, development, covering solutions to challenges regarding new developments, and regulatory and industry trends.

CONNECTIVITY

Thierry Decock

Nemera

CONNECTED DEVICES – MEDICATION DELIVERY JUST GOT PERSONAL

Thierry Decock and Hadrien Gremillet explore how the obstacles to the adoption of connectivity can be overcome and how connected devices can deliver truly patient-centric care that will clearly improve adherence rates, whilst demonstrating a clear cost benefit to the pharmaceutical partner.

WEARABLES

Jesper Roested

Subcuject

A PATIENT CENTRIC AND PHARMA COMPANY CENTRIC PREFILLED WEARABLE BOLUS INJECTOR

Jesper Roested explains why the pharma/biotech drug development process often means device selection occurs after Phase II despite the advantages of earlier selection being well understood, and how this then precludes the selection of novel primary packaging and delivery systems.

WEARABLES

Victoria Morgan

West Pharmaceutical Services

ALTERING PATIENT TREATMENT: HOW SC DELIVERY CAN HELP PATIENTS MANAGE CHRONIC CONDITIONS

Victoria Morgan looks at the benefits of combining an active pharmaceutical product with a novel subcutaneous delivery device, and highlights some of the partnerships West has with biopharmaceutical and other companies, which have led to market launches of products incorporating its on-body delivery system.

EXPERT VIEW

Jennifer Estep

PATIENT TOLERABILITY WITH HIGH-VISCOSITY, LARGE-VOLUME SUBCUTANEOUS INFUSIONS

Jennifer King and Matthew J Huddleston discuss the advantages of subcutaneous drug delivery and how these have yet to be fully harnessed in currently marketed therapeutics.

PREFILLED SYRINGES

Dr Eric Chappel

Debiotech

LOW-COST DISPOSABLE WEARABLE INJECTOR PLATFORM FOR LARGE VOLUMES OF VISCOUS DRUGS

Eric Chappel, Dimitry Dumont-Fillon and Laurent-Dominique Piveteau discuss Debiotech’s novel wearable injector technology, which utilises a propellant vapour system to drive the injection, making the device both space- and cost-efficient.

PREFILLED SYRINGES

Mindy Katz

Eitan Medical

UV STERILISATION & THE CASE FOR PREFILLED & PRELOADED DRUG DELIVERY SYSTEMS

Mindy Katz and Ori Ben-David review the different fill form configurations of drug delivery devices, outlining the importance of the prefilled and preloaded device configuration for self-administering patients.

EXPERT VIEW

Charlotte Harvey

HOW SAFETY FEATURES MAKE OR BREAK INFUSION PUMP DESIGN

Charlotte Harvey and Tim Frearson overview the safety systems required when designing an infusion pump system, with a focus on free-flow prevention, occlusion detection and air-in-line detection.

PREFILLED SYRINGES

Hans Peter Manser

Weibel CDS

LYCAJECT: AUTOMATIC RECONSTITUTION PATCH INJECTOR

Hans Peter Manser, Christoph Egloff and Martin C King introduce the LyCaJect Patch Injector, Weibel CDS’ offering in the field of wearable injectors, with automatic reconstitution as a headline feature.

WEARABLES

Mindy Katz

Eitan Medical

PREFILLED WEARABLE DRUG DELIVERY: HARNESSING TECHNOLOGY FOR PATIENT & PARTNER CENTRICITY

Mindy Katz describes in detail the company’s journey from identifying a clear market need to development and commercialisation of Sorrel’s prefilled and preloaded wearable injection device.

WEARABLES

Jesper Roested

Subcuject

WEARABLE INJECTORS: THE PERCEPTION OF INHERENT EXPENSE AND COMPLEXITY

There is a widespread belief that wearable injectors are too expensive and complex to really take off as a commercially viable method of drug delivery. Jesper Roested tackles the causes of this belief, and explains why it is not truly the case.

EXPERT VIEW

Paul Jansen

2014 TO 2018: AN UPDATE ON THE STATE OF WEARABLE INJECTORS

Looking back on the developments in large volume injectors since his article in ONdrugDelivery’s 2014 issue on wearable injectors, Paul Jansen reflects on the state of this technology space today, how it has progressed and the value it is likely to offer.

WEARABLES

Dr Jeannie Joughin

Enable Injections

BIOLOGIC DRUGS AND THEIR DELIVERY SYSTEMS: A SYMBIOSIS KEY TO COMMERCIAL SUCCESS

Jeannie Joughin discusses the ever-growing importance of the delivery system in the biologic combination product area, highlighting how it is the delivery system, not the drug, that defines the patient experience.

WEARABLES

Dr Paul Senn

Sensile Medical

CUSTOMISED SOLUTIONS FOR LARGE-VOLUME INJECTORS

Paul Senn discusses the products and philosophy of Sensile Medical, a developer of large volume injection devices utilising a patented micro pump technology.

WEARABLES

Ian Thompson

Ypsomed

YPSODOSE: SIMPLIFYING LARGE-VOLUME PATCH INJECTION FOR PHARMA COMPANIES AND PATIENTS

Ian Thompson provides an update on YpsoDose, a new prefilled large-volume patch injector platform, and how it is designed to simplify the approach to wearable patch injectors for both pharma companies and patients.

WEARABLES

Joe Reynolds

Noble

DEVICE TRAINING AND ONBOARDING CONSIDERATIONS FOR ON-BODY DELIVERY SYSTEMS

Joe Reynolds explains how on-body injection devices have arisen from the need to develop viscous, large-volume biopharmaceutical therapies, and how Noble’s on-body training devices can help patients learn how to use their devices correctly, reliably and safely.

WEARABLES

Graham Reynolds

West Pharmaceutical Services

THE CHANGING LANDSCAPE OF WEARABLE DRUG CONTAINMENT AND DELIVERY

Biologics and biosimilars are set to make waves in the pharmaceutical arena, but these drugs can be very difficult to deliver in a patient-centric way. Wearable injectors offer a solution to the large, infrequent dosing regimens these drugs often demand. Graham Reynolds explains more.

WEARABLES

Thomas Mayer

Sonceboz

DRUG DELIVERY MEETS AUTOMOTIVE ENGINEERING

Thomas Mayer discusses Sonceboz’s activity in the world of wearable injectors and how the company’s experiences in the automotive industry and its in-house development of high-quality motors provide significant advantages for the design and production of wearable devices.

EXPERT VIEW

Richard Featherstone

Emergo By UL

MOBILE DEVICES AND USE-RELATED RISK – TIME TO REINSTATE DETECTABILITY?

Richard Featherstone makes the case for designing detectability into the user interfaces of wearable devices, enabling the user to be an active part of ensuring the device operates safely, as intended.

WEARABLES

Claudia Fink

Raumedic

INSERT. WEAR. INJECT. DISPOSABLE UNITS FOR WEARABLE DRUG DELIVERY DEVICES

Mobile drug delivery pumps can significantly improve patients’ quality of life, however they require highly advanced disposable components to ensure that patients receive the exact dose required. Claudia Fink reviews how the components are produced and which secondary processing techniques are required and Raumedic's partnership with Sensile Medical.

WEARABLES

John Love

Enable Injections

ENABLE INJECTIONS AND FLEX SET AMBITIOUS PLANS FOR LARGE VOLUME DRUG DELIVERY

The delivery of high volumes of biologics outside of the clinical setting remains a key challenge in the industry. Here, John Love, Mark Lee and Amy Boyle discuss how the enFuse™ on-body injector, developed by Enable in partnership with Flex, may be the answer.