Pulmonary & Nasal Delivery85

Issue No #85 April 16th, 2018

Issue 85 - Apr 2018

Inside the magazine

A POSITIVE SPIN ON DPI FORMULATION

A POSITIVE SPIN ON DPI FORMULATION

Bert Dekens outlines some of the considerations that go into developing and processing dry powder inhaler formulations, and discusses the merits of conical high-shear mixers.

POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY

Dr Karlheinz Seyfang

POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY

Karlheinz Seyfang discusses the need for filling verification in pre-metered DPI blister filling lines, going on to detail the role X-ray analysis could play in an automated verification process.

COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING

Proveris Scientific

COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING

Heli Chauhan outlines the major challenges encountered in testing pressurised metered dose inhalers, and how Proveris’ portfolio of instruments can be an invaluable addition to the testing workflow.

DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM

DRUG REPURPOSING – BROADENING PATIENT ACCESSIBILITY VIA A CHANGE IN DRUG DELIVERY SYSTEM

Badre Hammond, Gerallt Williams and Herve Pacaud discuss the growing trend of drug repurposing.

INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION

INFLUENCE OF THE HUMAN FACTOR ON NASAL DRUG DELIVERY DEVICE EVALUATION

Pascale Farjas, Alain Regard and Guillaume Grevin, discuss what is required of a modern nasal spray pump and how introducing the human factor showed a significant impact on the variability of delivered volume.

REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS

REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS

Craig Baker discusses the prevalence of improper use and how addressing this issue via training devices is of benefit to manufacturers, healthcare providers and patients.

THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES

THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES

Mary Hutchens gives an overview of some of the changes wrought by last year’s introduction of the new EU Medical Device Regulation, with a specific view to its effect on inhalation devices and inhaled medical products.

CHOOSING THE RIGHT DOSATOR FOR DPI DOSING

CHOOSING THE RIGHT DOSATOR FOR DPI DOSING

Jamie Clayton, Rajeev Dattani and Dave Seaward discuss the operation of dosators for reliable and accurate filling of DPI capsules and blisters.

MEETING FUTURE NEEDS FOR RESPIRATORY DRUG DELIVERY DEVELOPMENT

MEETING FUTURE NEEDS FOR RESPIRATORY DRUG DELIVERY DEVELOPMENT

Mark Knowles and Collette Johnson explore the different elements that need to be considered when developing a smart inhalation drug delivery device to ensure that maximum benefit is obtained.

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