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INJECTION

SUSTAINABILITY
SUSTAINABLE GLP-1 DRUG DELIVERY: FUTURE-PROOFING THERAPY ADMINISTRATION FOR OBESITY AND BEYOND
Lorenzo Biasio and Gloria Skibba discuss the integration of Ypsomed’s Net Zero Program into its self-injection platforms. With the evolution of GLP-1 therapies and the exploration of higher-dose formulations, the demand for higher-volume autoinjectors is increasing; this article explains how Ypsomed has also applied its sustainability principles to larger-volume delivery.
INJECTION
HIGH-DOSE DRUG DELIVERY – HOW FAR CAN AUTOINJECTORS GO?
Iain Simpson reviews the development of autoinjectors for self-injection and explains that, despite significant emerging trends for biologics, new developments in formulation and autoinjector technology may enable them to continue to be the dominant delivery device for these medications.
A Sustainable Future for Self-Injection with Connected, Reusable Autoinjectors
INTERVIEW
Dr Patrick Anquetil
Portal Instruments
A Sustainable Future for Self-Injection with Connected, Reusable Autoinjectors
In this exclusive interview with ONdrugDelivery’s Guy Furness, Dr Patrick Anquetil offers insight into the extensive waste involved in the self-injection market. He explains how pivoting from a model focused on fully disposable devices to reusable electromechanical autoinjectors could offer a more sustainable and cost-effective path forward.
UNDERSTANDING PATIENT PREFERENCES FOR SUSTAINABLE ON-BODY DELIVERY SYSTEMS
SUSTAINABILITY
Stevanato Group
UNDERSTANDING PATIENT PREFERENCES FOR SUSTAINABLE ON-BODY DELIVERY SYSTEMS
Stevanato Group examines how semi-reusable, modular designs like its Vertiva 10 mL on-body delivery system can reconcile patient demands for ease of use with growing expectations for sustainability, sharing new UK preference data and lifecycle analysis that reveal significant waste and emissions reductions.
A COMPREHENSIVE APPROACH TO ADDRESSING UNMET NEEDS IN INTRAVITREAL INJECTIONS
OCULAR
Dr Reza Abedian
Gerresheimer
A COMPREHENSIVE APPROACH TO ADDRESSING UNMET NEEDS IN INTRAVITREAL INJECTIONS
Dr Reza Abedian, Marie Stockton and Bernd Zeiss consider the complexities and clinical unmet needs of intravitreal injections and discuss how Gerresheimer’s syringe technology can help overcome these challenges.
GENE THERAPY IN OPHTHALMOLOGY: ADVANCES AND CHALLENGES
EXPERT VIEW
Dr Joe Batley
GENE THERAPY IN OPHTHALMOLOGY: ADVANCES AND CHALLENGES
Joe Batley and Lorna Barron provide an overview of the latest cutting-edge ophthalmic delivery methods and discuss possible future developments.
A NEW DELIVERY PLATFORM FOR SUPRACHOROIDAL ADMINISTRATION USING WEST’S ADVANCEABLE MICRONEEDLE DEVICE
OCULAR
Dr Anu Prabhathachandran
West Pharmaceutical Services
A NEW DELIVERY PLATFORM FOR SUPRACHOROIDAL ADMINISTRATION USING WEST’S ADVANCEABLE MICRONEEDLE DEVICE
Anu Prabhathachandran, Menachem Peretz and Manali Potnis discuss the growing need for more effective delivery of ophthalmic therapeutics to meet the needs of the ageing population, including how delivery into the suprachoroidal space may present an appealing alternative to intravitreal injection. They introduce West Pharmaceutical Service’ Suprachoroidal Advanceable Microneedle Device, which offers several advantages for overcoming the challenges with suprachoroidal space.
INTRODUCING THE TERUMO INJECTION FILTER NEEDLE – A FIRST STEP OF THE INFINO™ DEVELOPMENT PROGRAMME
INJECTION
Thomas Isaac
Terumo Medical Care Solutions
INTRODUCING THE TERUMO INJECTION FILTER NEEDLE – A FIRST STEP OF THE INFINO™ DEVELOPMENT PROGRAMME
Thomas Isaac considers the issues associated with injection to highly sensitive areas, such as the vitreous body, and the potential to optimise needle design and features to address these issues, discussing the key features of Terumo’s Injection Filter Needle, indicated for hypodermic and intravitreal injections within this context.
THE RISE OF LARGE-VOLUME SUBCUTANEOUS ADMINISTRATION OF BIOPHARMACEUTICALS, AND DELIVERY IMPLICATIONS
INJECTION
Dr Andreas Schneider
Ypsomed
THE RISE OF LARGE-VOLUME SUBCUTANEOUS ADMINISTRATION OF BIOPHARMACEUTICALS, AND DELIVERY IMPLICATIONS
Andreas Schneider and Jakob Lange consider the SC administration of larger volumes of biopharmaceuticals in the pharma industry and summarise a recent study that reviews clinical-stage and approved IV and SC biopharmaceuticals to provide valuable guidance for new product development, as well as for marketing and commercialisation strategies in the rapidly evolving large-volume SC landscape.
CONTAINER SELECTION FOR A HIGHLY SENSITIVE DRUG PRODUCT: A SUCCESS STORY
INJECTION
Enrico Barichello
Stevanato Group
CONTAINER SELECTION FOR A HIGHLY SENSITIVE DRUG PRODUCT: A SUCCESS STORY
Enrico Barichello discusses Stevanato Group’s collaboration with a leading pharmaceutical company to identify a suitable container for a high-concentration monoclonal antibody. The partnership addressed key challenges and contributed to maintaining the drug’s stability and integrity throughout its lifecycle.
DRUG DELIVERY TRENDS FOR 2025
EXPERT VIEW
Tom Oakley
DRUG DELIVERY TRENDS FOR 2025
Tom Oakley and Alex Vasiev look back at how the trends anticipated for 2024 played out in reality and look forward to four major trends expected to influence the drug delivery industry in 2025.
EMPOWERING PHARMA WITH INNOVATIVE INFUSION TECHNOLOGIES AMID US POLICY CHANGES
INJECTION
Mindy Katz
Eitan Medical
EMPOWERING PHARMA WITH INNOVATIVE INFUSION TECHNOLOGIES AMID US POLICY CHANGES
Mindy Katz and Michael Ratigan outline the implications for pharmaceutical manufacturers of recent US policy changes – and highlight how Eitan Medical’s portfolio of infusion solutions can offer support.
510(k) CLEARED, USER-FILLED MICRODOSING DEVICE FOR OPHTHALMIC AND OTHER APPLICATIONS
PREFILLED SYRINGES
Dr Gautam Shetty
Congruence Medical Solutions
510(k) CLEARED, USER-FILLED MICRODOSING DEVICE FOR OPHTHALMIC AND OTHER APPLICATIONS
Gautam Shetty discusses unmet drug delivery needs in applications requiring accurate and precise microlitre-scale doses,going on to detail how the Congruence Medical’s recently cleared Microliter Dosing Syringe can bring the benefits of advanced syringe materials and performance to these applications.
TUB & NEST – PRECISION AND EFFICIENCY IN DRUG DELIVERY
PREFILLED SYRINGES
Ivana Thiesson
Fischer Söhne
TUB & NEST – PRECISION AND EFFICIENCY IN DRUG DELIVERY
Ivana Thiesson and Jörg Sander applied marketing discuss the benefits of Fischer Söhne’s “Tub & Nest” format for packaging prefilled syringes, including design flexibility and precise cleanroom manufacturing.
UNLOCK VALUE: KEY COST DRIVERS IN SPRING AND STAMPING DESIGN
INDUSTRIALISATION
Rolando Abaroa Martinez
Baumann Medical
UNLOCK VALUE: KEY COST DRIVERS IN SPRING AND STAMPING DESIGN
Rolando Abaroa Martinez and David Pircher highlight how a metal parts supplier can help to optimise costs – not only for springs and stampings but also in later production stages of a medical device. With a focus on the design phase, they emphasise that not only the costs associated with the metal product but also the total costs can be managed effectively with the right support from experts.
THE ROLE OF METAL DEEP-DRAWN PARTS IN MEDICAL DEVICES FOR DRUG DELIVERY
INDUSTRIALISATION
Dennis Gossmann
STÜKEN Medical
THE ROLE OF METAL DEEP-DRAWN PARTS IN MEDICAL DEVICES FOR DRUG DELIVERY
Dennis Gossmann discusses the benefits of using deep-drawn metal components in drug delivery devices and how STÜKEN MEDICAL, as an established expert in this field, can be an ideal partner for manufacturing and supplying these parts.
TESTING SYRINGES & INJECTION DEVICES: SOLUTIONS THAT BOOST EFFICIENCY
INJECTION
Peter Schmidt
ZwickRoell
TESTING SYRINGES & INJECTION DEVICES: SOLUTIONS THAT BOOST EFFICIENCY
Peter Schmidt discusses ZwickRoell’s offerings in the arena of testing systems for injectable drug delivery systems, in particular highlighting the advantages of automation for providing reliable, reproducible results.
FROM PLATFORM TO PRODUCT: ACCELERATING TIME-TO-MARKET FOR PLATFORM TECHNOLOGIES
EXPERT VIEW
Fran Pencliffe
FROM PLATFORM TO PRODUCT: ACCELERATING TIME-TO-MARKET FOR PLATFORM TECHNOLOGIES
Fran Pencliffe explores the benefits of platform devices for parenteral delivery and outlines the challenges, risks and best practices when bringing a combination product to market in this way.
NOVEL SOLUTIONS FOR ULTRA-LARGE-VOLUME WEARABLE AND PORTABLE SUBCUTANEOUS INJECTORS
WEARABLES
Dr Hong-Jun Yeh
MicroMED Co Ltd
NOVEL SOLUTIONS FOR ULTRA-LARGE-VOLUME WEARABLE AND PORTABLE SUBCUTANEOUS INJECTORS
Dr Hong-Jun Yeh, Jiunn-Ru Lai and Tsung-Chieh Cheng discuss the need for novel approaches to the challenge of delivering high volumes of biologics while also addressing patient centricity, and introduce MicroMED’s two innovative gas-powered approaches that leverage micro-electromechanical systems to drive the injection.
Interview: Sustainability at the Heart of Aptar Pharma’s Expansion
INTERVIEW
Audrey Chardonnet
Aptar Pharma
Interview: Sustainability at the Heart of Aptar Pharma’s Expansion
Audrey Chardonnet discusses the centrality of sustainability to Aptar Pharma’s expansion strategy, going into detail on how, by improving its practices and investing in its infrastructure, the company works towards reducing the environmental impact of injectable drug delivery solutions manufacturing.
DEVICE SELECTION: INJECTION VOLUMES FOR SUBCUTANEOUS ADMINISTRATION
INJECTION
Dr Nicolas Brandes
ten23 health
DEVICE SELECTION: INJECTION VOLUMES FOR SUBCUTANEOUS ADMINISTRATION
Nicolas Brandes, Andrea Allmendinger and Hanns-Christian Mahler explore the critical considerations for subcutaneous injection volume, beginning with the historical and scientific perspectives on injection volume before delving into the challenges of determining volume ranges and their associated fill volumes.
VERSATILITY, SUSTAINABILITY AND DIGITALISATION IN ONE SMART HANDHELD INJECTION PLATFORM
INJECTION
Dr Leonard Chu
Altek Medical
VERSATILITY, SUSTAINABILITY AND DIGITALISATION IN ONE SMART HANDHELD INJECTION PLATFORM
Leonard Chu discusses three trends in self-administration that are aligned with emerging smart devices – device versatility, sustainability and digitalisation – and the benefits offered by the Alcee injection platform.
ELEVATING DIGITAL PATIENT SUPPORT: NOTHING MATTERS UNLESS IT CHANGES BEHAVIOUR
EXPERT VIEW
Dr Ben Cox
ELEVATING DIGITAL PATIENT SUPPORT: NOTHING MATTERS UNLESS IT CHANGES BEHAVIOUR
Ben Cox, Thomas Grant and Lara Zaki discuss the role of behaviour design in onboarding for self-injection devices and how a robust and balanced framework can enhance the patient experience, reduce injection errors and promote safe and effective use.
PICCOJECT – ADVANCING SELF-INJECTION OF HIGH-VISCOSITY FORMULATIONS
INJECTION
Thomas Thueer
Haselmeier
PICCOJECT – ADVANCING SELF-INJECTION OF HIGH-VISCOSITY FORMULATIONS
Thomas Thueer, Chris Muenzer and Stefanie Manger discuss the challenges posed to drug delivery device designers by the needs of biologic therapies. In response, Haselmeier has developed the PiccoJect autoinjector, which has a novel parallel spring layout that enables a newfound flexibility in design, ideally positioning it to rise to the challenges of delivering high-viscosity biologics.
BONDING TECHNOLOGIES FOR INJECTION DEVICES – A QUICK OVERVIEW
INDUSTRIALISATION
Hisham Jamal
teamtechnik
BONDING TECHNOLOGIES FOR INJECTION DEVICES – A QUICK OVERVIEW
Hisham Jamal and Carsten Köhler discuss some of the bonding technologies used for medical devices – highlighting their unique strengths, limitations and suitability.
NEXT-GENERATION AUTOINJECTORS: BALANCING PATIENTS, PHARMA, PAYERS AND PLANET
EXPERT VIEW
David Latham
NEXT-GENERATION AUTOINJECTORS: BALANCING PATIENTS, PHARMA, PAYERS AND PLANET
David Latham, Matthew Allen and Charlie Dean use a case study of a reusable electromechanical autoinjector to outline the novel product development approach needed to achieve better outcomes for patients, pharma, payers and the planet.
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