Inside the magazine
Jeannie Joughin describes how significant factors and developments have converged leading to the rise of patient-centric healthcare and self-administration, the wearable injector at the cutting edge. Also showing that early clinical partnership with a platform wearable device company is beneficial across numerous criteria, and how this was a key design consideration for Enable’s wearable technology.
Innovations in self-administered drug delivery systems are transitioning care out of hospitals and clinical settings into the home. To ensure patient compliance with treatment is maintained, an easy-to-use self-administration system can be key. Chris Henshall discusses the factors manufacturers should consider to ensure self-injected therapies meet patients’ needs and therefore improve patient outcomes.
Beth DiLauri sets out the fundamental case for the adoption of wearable injectors, outlines the specific barriers they overcome and describes how the design and development of the BD Libertas™ wearable injector platform, paired with the company’s unparalleled parenteral delivery device experience, make BD Libertas™ an attractive proposal for pharma companies seeking a wearable injector.
The development of fully automated, closed-loop glucose monitoring and insulin delivery systems can closely mimic a real pancreas. However, since the patient is not directly involved in administering the dose, these devices depend on one key factor - dosing accuracy. Jackson Thornton and Vinay Sakhrani examine how lubricant selection in the insulin cartridge, typically an afterthought, can make the delivery device more accurate.
New delivery systems for larger volume and more complex drugs, such as wearable injectors, are revolutionising patient treatment. However, research has shown that patients need to receive quality training and onboarding to ensure they use the devices properly and retain the information. Joe Reynolds explores the factors that need to be considered in developing optimal training devices for patients.
While autoinjectors are often the delivery method of choice for patient self-administration, there are occasions when a vial and syringe format is required. To overcome the problems associated with this method, Medicom has developed a flexible, wearable patch pump which can accept a simple glass vial and provide a fully automated injection system. Hans Jensen and Kate Hudson-Farmer explain how it works.
Chief Executive Officer Derek Brandt and three of his colleagues – Christoph Lüdi, Head of Systems Engineering, Alex Perrier, Senior Technology Manager, and Marco Drüssel, Mechanical Engineering Manager – have all been a part of Sensile Medical for the past ten years, and here reflect on the company’s past and discuss the future.