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EXPERT VIEW

RETHINKING PLASTIC: HOW ECO-FRIENDLY DESIGN IS DRIVING SUSTAINABLE CHANGE
EXPERT VIEW
Giorgio Sardo
RETHINKING PLASTIC: HOW ECO-FRIENDLY DESIGN IS DRIVING SUSTAINABLE CHANGE
Giorgio Sardo discusses sustainable material selection and the results of tests comparing the performance of sustainable bio-based plastic resins with their fossil-based equivalents.
DESIGNING SUSTAINABILITY INTO PHARMACEUTICAL DEVICES
EXPERT VIEW
Will Davies
DESIGNING SUSTAINABILITY INTO PHARMACEUTICAL DEVICES
Will Davies discusses in detail how to address the challenges of designing sustainability into pharmaceutical devices.
SUSTAINABILITY IN DRUG DELIVERY: HOW DO WE GET THERE?
EXPERT VIEW
Tim Wooller
SUSTAINABILITY IN DRUG DELIVERY: HOW DO WE GET THERE?
Tim Wooller discusses the urgent need to transition away from disposable models of drug delivery device design and move towards reusables, providing insights into the reasons why and the methods by which this can be achieved.
IMPROVING RECYCLABILITY IN DRUG DELIVERY
EXPERT VIEW
Julien Tremblin
IMPROVING RECYCLABILITY IN DRUG DELIVERY
Julien Tremblin looks at the recyclability challenges facing the drug delivery market and considers how companies can enhance the recyclability of their packaging and devices.
DUE DILIGENCE – THE KEY TO SUCCESS IN DRUG DELIVERY DEVICE SELECTION
EXPERT VIEW
Matt Jones
DCA
DUE DILIGENCE – THE KEY TO SUCCESS IN DRUG DELIVERY DEVICE SELECTION
Matt Jones and Rob Veasey consider the process of matching the drug with the right delivery device and look at the importance of due diligence when “licensing in” technology.
CONSIDERATIONS WHEN SWITCHING FROM CURRENT pMDI PROPELLANTS TO NEW LOWER-GWP PROPELLANTS
EXPERT VIEW
Mark Parry
CONSIDERATIONS WHEN SWITCHING FROM CURRENT pMDI PROPELLANTS TO NEW LOWER-GWP PROPELLANTS
Mark Parry discusses the considerations that need to be made when switching from current pressurised metered dose inhaler propellants to new alternatives with lower global warming potential, including formulation, regulatory and analytical standpoints.
THE NEXT GENERATION OF MICRONEEDLES: HARNESSING A BILLION YEARS OF EVOLUTION
EXPERT VIEW
Dr Gabriel Villar
THE NEXT GENERATION OF MICRONEEDLES: HARNESSING A BILLION YEARS OF EVOLUTION
Gabriel Villar and Ethan Miller consider examples of nature’s solutions to four challenges faced by microneedles for drug delivery. For each challenge, the authors explain how a natural organism has tackled it and what lessons may be directly applied to microneedle design.
OVERCOMING CHALLENGES WHEN DEVELOPING OLIGONUCLEOTIDES FOR OPHTHALMIC DRUGS
EXPERT VIEW
Dr Shiyan Chen
OVERCOMING CHALLENGES WHEN DEVELOPING OLIGONUCLEOTIDES FOR OPHTHALMIC DRUGS
Shiyan Chen and Binbin Tian discuss the use of oligonucleotides for ophthalmic applications, including their potential uses, advantages, challenges and difficulties when it comes to pharmacokinetic and drug metabolism studies.
TOPICAL DRUG ADMINISTRATION FOR THE POSTERIOR SEGMENT
EXPERT VIEW
Dr David Bingaman
TOPICAL DRUG ADMINISTRATION FOR THE POSTERIOR SEGMENT
David Bingaman explores the potential benefits of topical administration for diseases affecting the posterior segment of the eye.
BEYOND THE EYEDROPPER BOTTLE – THREE WAYS TO IMPROVE ADHERENCE
EXPERT VIEW
Dr Nathan Wilkinson
BEYOND THE EYEDROPPER BOTTLE – THREE WAYS TO IMPROVE ADHERENCE
Nathan Wilkinson, Catherine Wyman and Matt Parker discuss the future outlook of ophthalmic drug delivery beyond the traditional eyedropper bottle, including new delivery technologies, sustained-release therapeutics and digital healthcare applications.
A SIGHT FOR SORE EYES: CHALLENGES & INNOVATIONS IN OPHTHALMIC DRUG DELIVERY
EXPERT VIEW
Dr Ethan Miller
A SIGHT FOR SORE EYES: CHALLENGES & INNOVATIONS IN OPHTHALMIC DRUG DELIVERY
Ethan Miller and Kristien De Clercq discuss recent advancements and current challenges in the field of ophthalmology, including the trend towards preservative-free multidose delivery systems, delivering smaller topical volumes with increased drug efficacy, slow-release injections for delivery to the posterior of the eye and the exciting field of gene therapy.
EXTRACTABLES/LEACHABLES TESTING CONSIDERATIONS FOR SINGLE-USE SYSTEMS
EXPERT VIEW
Sandi Schaible
EXTRACTABLES/LEACHABLES TESTING CONSIDERATIONS FOR SINGLE-USE SYSTEMS
Sandi Schaible discusses testing considerations for extractables and leachables along with the regulatory environment for single-use systems.
CONNECTED DRUG DELIVERY DEVICES: BENEFITS AND CYBERSECURITY
EXPERT VIEW
João Budzinski
CONNECTED DRUG DELIVERY DEVICES: BENEFITS AND CYBERSECURITY
João Budzinski discusses the benefits of connected drug delivery devices and the importance of cybersecurity when developing them, including the threats, key considerations and potential solutions.
EXPANDING THE DESIGN OF CHARACTERISATION STUDIES FOR ACCURATE HANDLING-ERROR ASSESSMENT
EXPERT VIEW
Dr Yannick Baschung
EXPANDING THE DESIGN OF CHARACTERISATION STUDIES FOR ACCURATE HANDLING-ERROR ASSESSMENT
Yannick Baschung discusses the importance of a comprehensive and accurate assessment of patient handling errors when it comes to inhaled product development.
THE INFLUENCE OF UNCERTAINTY ON CHEMICAL CHARACTERISATION
EXPERT VIEW
James Silk
THE INFLUENCE OF UNCERTAINTY ON CHEMICAL CHARACTERISATION
James Silk discusses the importance of accounting for uncertainty when characterising the extractables profile of a medication, with particular reference to the ISO 10993 standard.
THE INNOVATIONS TACKLING CHALLENGES & MAXIMISING OPPORTUNITIES IN INHALATION
EXPERT VIEW
Marco Franza
THE INNOVATIONS TACKLING CHALLENGES & MAXIMISING OPPORTUNITIES IN INHALATION
Marco Franza and Nadine Khoury look at how the latest digital technologies, manufacturing techniques and packaging materials are combining to take the manufacture of inhalers to a new level.
TAKING THE STING OUT OF VACCINES
EXPERT VIEW
Dr Heather Jameson
TAKING THE STING OUT OF VACCINES
Heather Jameson, Juliette Ngan and Omar Shah discuss the potential advantages and challenges of intranasal and inhaled vaccines in the context of global respiratory pandemics.
SOLVING COMPLEX FORMULATION & DELIVERY CHALLENGES FOR INTRANASAL DRUGS
EXPERT VIEW
Dr Paul Kippax
SOLVING COMPLEX FORMULATION & DELIVERY CHALLENGES FOR INTRANASAL DRUGS
Paul Kippax discusses the analytical techniques used for in vitro characterisation of nasal sprays, and how their use can accelerate and de-risk both innovator and generic nasal drug development.
NASAL DELIVERY – A GALAXY NOT SO FAR AWAY… A BRIEF MARKET HISTORY OF THE NASAL DELIVERY LANDSCAPE
EXPERT VIEW
Mark Ignaczak
NASAL DELIVERY – A GALAXY NOT SO FAR AWAY… A BRIEF MARKET HISTORY OF THE NASAL DELIVERY LANDSCAPE
Mark Ignaczak provides an insight into the history of nasal drug delivery and looks at the advantages of the nasal delivery route.
SUSTAINABLE DESIGN & MANUFACTURE IN MEDICAL DEVICES: WHERE TO START
EXPERT VIEW
Cormac O'Prey
SUSTAINABLE DESIGN & MANUFACTURE IN MEDICAL DEVICES: WHERE TO START
Cormac O’Prey discusses the challenges and advantages of implementing circular economy principles in the medical device sector, with a particular consideration of the difficulty of making remanufacturing work for high-volume, low-value devices.
THE ENVIRONMENTAL IMPACT OF GLOBAL SUPPLY CHAIN LOGISTICS & SUPPLIER SELECTION
EXPERT VIEW
Alastair Willoughby
THE ENVIRONMENTAL IMPACT OF GLOBAL SUPPLY CHAIN LOGISTICS & SUPPLIER SELECTION
Alastair Willoughby looks at the factors affecting sustainability when considering global supply chain logistics and supplier selection.
CLIMATE CHANGE AND THE PHARMACEUTICAL INDUSTRY: TOO LITTLE, TOO LATE?
EXPERT VIEW
Catriona Eldridge
CLIMATE CHANGE AND THE PHARMACEUTICAL INDUSTRY: TOO LITTLE, TOO LATE?
Catriona Eldridge and Omar Shah discuss the findings of a recent investigative assessment into the environmental impact of healthcare products, and consider whether or not the pharmaceutical industry is doing enough to combat climate change.
AUTOINJECTORS: HISTORICAL ACHIEVEMENTS & COMPELLING NEEDS DRIVING NEXT-GENERATION DEVICES
EXPERT VIEW
Richard Whelton
AUTOINJECTORS: HISTORICAL ACHIEVEMENTS & COMPELLING NEEDS DRIVING NEXT-GENERATION DEVICES
Richard Whelton and Philip Green summarise the history of autoinjectors, highlight success stories to date, review the unmet needs that remain and consider emerging needs that could drive continued innovation in autoinjectors to ensure safety, patient satisfaction and pharma commercial success.
ON-BODY DELIVERY SYSTEMS – NEWS AND TRENDS
EXPERT VIEW
Tom Oakley
ON-BODY DELIVERY SYSTEMS – NEWS AND TRENDS
Tom Oakley discusses the current state of play in the on-body delivery system space, reviews recent milestones and proposes directions for the future.
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