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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
CONTRIBUTE
MEDIA PACK
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GI/ORAL
GI/ORAL
ROLLER COMPACTION IN MODERN ORAL SOLID DOSE DEVELOPMENT
David O’Connell delves into oral solid dosage production, highlighting the advantages of roller compaction for sensitive drugs as well as the possibilities for integration into existing manufacturing lines.
GI/ORAL
INTELLIGENT INTEGRATION: WHY CONNECTED OSD ECOSYSTEMS ARE RESHAPING PHARMACEUTICAL MANUFACTURING
Borja Guerra delves into how the oral solid dosage manufacturing industry is being reshaped by connected machinery, advanced digital systems and integrated supplier ecosystems across the production process.
GI/ORAL
Derek Beauchamp
Catalent Pharma Solutions
MICRONISATION SUCCESS STARTS WITH SOLID-STATE UNDERSTANDING
Dr Derek Beauchamp and John Kusnierz explain how solid-state characterisation underpins the behaviour of a drug substance under processing conditions, and consider the importance of micronisation in improving bioavailability and drug product performance.
EXPERT VIEW
Dr Sahab Babaee
ORAL DELIVERY OF MACROMOLECULES: CHALLENGES AND OPPORTUNITIES FOR DEVICE-ENABLED GI DELIVERY
Dr Sahab Babaee discusses the potential of device-based approaches to enable the delivery of macromolecules via the gastrointestinal tract, considering the constraints and possibilities of mucosal delivery devices, as well as the technologies currently being investigated to make this potential a reality.
GI/ORAL
Dr Vincent Jannin
Lonza Capsugel
ADVANCING ORAL BIOLOGIC DELIVERY: OVERCOMING BARRIERS TO ENABLE INNOVATION AND ACCESS
Dr Vincent Jannin considers the advantages of delivering biologic medications, including glucagon-like peptide-1s, via oral delivery and discusses the technological strides being made towards enabling biologics to shift away from parenteral delivery.
EXPERT VIEW
Tom Oakley
TRENDS FOR 2026
A new reality is forming as we enter 2026 – it will not be “business as usual”. Geopolitical forces in the largest market for pharmaceuticals, the US, are likely to mean substantial changes. Here, Tom Oakley and Alex Vasiev cover those changes, the incretin juggernaut and the march of technical progress with “minitablet” dispensers, large-volume injectors and dual-chamber devices.
FORMULATION
Dr Liliana Miinea
Lubrizol
FROM BRICK-DUST DRUGS TO BREAKTHROUGHS: TRANSFORMING DRUG DELIVERY WITH NOVEL EXCIPIENTS
Dr Liliana Miinea of Lubrizol discusses how next-generation excipients can help formulators realise the potential of promising but poorly soluble drug candidates, including Lubrizol’s Apisolex™ and Apinovex™ polymer excipients for parenteral and oral applications.
INTERVIEW
Dr Keat Theng Chow
Roquette
Interview: Patient Experience Versus Regulatory Compliance – Can Formulators Find a Middle Ground?
Dr Keat Theng Chow outlines the essential themes on Roquette’s radar regarding patient-centric drug design, upcoming regulatory changes and how drug producers can navigate both spheres to the benefit of all.
GI/ORAL
Dr Anshul Gupte
PCI Pharma Services
TPDs: DEVELOPING THE NEXT GENERATION OF ORAL THERAPEUTICS
Dr Anshul Gupte looks at how targeted protein degraders are redefining the landscape of drug delivery, creating new strategies for previously untreatable diseases. The article goes on to consider the scientific, manufacturing and regulatory challenges ahead, while considering the role specialised CDMOs can play in overcoming these obstacles.
GI/ORAL
Anna Kirstine Jørgensen
FabRx
3D PRINTING: THE FUTURE OF PERSONALISED MEDICINES
Anna Kirstine Jørgensen, Dr Abdul Basit along with Dr Alvaro Goyanes, discuss the role of 3D printing in shaping the future of personalised medication, and explain how FABRX’s two pharmaceutical 3D printers can help unlock its potential – extending even beyond Earth.
GI/ORAL
Thierry Jomini
AbbatiaLabs
ENHANCING PERSONALISED MEDICINE: POWDOSE AND DIFFUCAPS FOR PRECISE ORAL SOLID DOSING
Thierry Jomini, Stéphane Baronnet, Dr John van den Anker along with Giuseppe De Franza, evaluate the performance of the POWDOSE
®
system in delivering precise and repeatable doses of different formulations of Diffucaps
®
. The authors analyse the functionalities of combining Diffucaps with POWDOSE and highlighting its potential for improving personalised dosing regimens.
EXPERT VIEW
Dr Maj-Britt Cepok
A STICKY ISSUE: TRANSFORMING OILY PLANT EXTRACTS INTO SOLID ORAL DOSAGE FORMS
Dr Maj-Britt Cepok discusses the increasing prevalence of plant extracts in the oral solid dosage market, considering how the common physical properties of these ingredients can both provide benefits and pose a challenge to formulators looking to capitalise on this rapidly growing market segment.
CONNECTIVITY
Sylvia Kaiser
NXP Semiconductors
DIGITAL TWINS – A RAPIDLY GROWING TREND IN HEALTHCARE
Sylvia Kaiser-Kershaw, Susanne Hazrati and Sebastian Muenscher examine how digital twinning, based on smart and secure wirelessly connected tags and labels, can transform healthcare processes.
GI/ORAL
Lucia Gurruchaga
Qualicaps
NAVIGATING THE TRANSITION: EXPLORING ALTERNATIVES TO TiO
2
IN PHARMACEUTICAL FORMULATIONS
Lucía Gurruchaga discusses the push to develop an alternative opacifier and white colourant to titanium dioxide in the wake of the European Commission’s announcement that the additive may be banned in medicinal products, presenting data from recent testing on Qualicaps’ own novel alternative.
GI/ORAL
Ivy Comer
Aptar Active Material Science
TARGETING NITROSAMINE PRECURSORS WITH NOVEL ACTIVE MATERIAL SCIENCE SCAVENGER TECHNOLOGIES
Ivy Comer, Amanda Murph and Jason Pratt, discuss the challenges in combatting N-nitrosamine formation in oral solid dosage forms, and present Aptar’s 3-Phase Activ-Polymer technology as a novel packaging-based solution.
EARLY INSIGHT
Dr Buddhadev Chaudhuri
Keylika
TACKLING IRON-DEFICIENCY ANAEMIA: A LEAP FORWARD WITH A REVOLUTIONARY BUCCAL PATCH
Buddhadev P Chaudhuri and Frederik Ceyssens, discuss the challenges of iron-deficiency anaemia and introduce Keylika’s new buccal patch for iron delivery.
EXPERT VIEW
Jason Hunt
ADAPTING TO AN AGEING WORLD: FORMULATION STRATEGIES TO BOOST PATIENT COMPLIANCE
Jason Hunt and Yeli Zhang discuss the key factors undermining patient compliance in older adults and explore how the pharmaceutical industry can leverage excipients to enhance drug formulations and improve medication compliance among this critical demographic.
EXPERT VIEW
Nigel Theobald
ARE ORAL FORMULATIONS OF OLIGONUCLEOTIDE THERAPEUTICS WITHIN REACH?
Nigel Theobald, discusses key issues and strategies for formulation scientists aiming to unlock the potential of oral delivery for small interfering ribonucleic acid drugs targeted against gastrointestinal diseases and cancers.
EXPERT VIEW
Mariona Venceslao Molins
DIFFERENTIATING ORAL SUSPENSIONS WITH VERSATILE EXCIPIENTS
Mariona Venceslao Molins and Liliana Miinea discuss how excipient-based approaches can facilitate patient-centric formulations and transform oral suspensions.
EXPERT VIEW
Dr Jnanadeva Bhat
STRATEGIES TO MITIGATE GELATIN CROSS-LINKING IN ORAL SOLID DRUG DELIVERY
Jnanadeva Bhat and Manali Dalvi discuss the factors contributing to gelatin cross-linking in oral solid dose delivery – and strategies to tackle the resulting challenges.
EXPERT VIEW
Dr Zdravka Misic
CANNABIDIOL DELIVERY THAT IS ON THE “TIP OF THE TONGUE”
Zdravka Misic explores how formulation expertise can be applied to overcome the low bioavailability of cannabinoids and how innovation in orally disintegrating tablets is driving progress for cannabidiol-based therapeutics.
GI/ORAL
Dr Keat Theng Chow
Roquette
TREATING THE NEXT GENERATION: THE UNTAPPED POTENTIAL OF ORALLY DISPERSIBLE FILMS
Keat Theng Chow explores the latest scientific thinking on orally dispersible film formulation, and how these advancements could open a new chapter in paediatric patient compliance.
GI/ORAL
Susana Ecenarro
Qualicaps
CHALLENGES AND ACHIEVEMENTS OF TIO
2
REPLACEMENT IN HARD CAPSULES
Susana Ecenarro Probst looks at the issues arising in replacing TiO
2
in hard capsules and introduces Qualicaps' alternative hard capsule formulation.
GI/ORAL
Dr Bettina Hölzer
Evonik
PRODUCT SHOWCASE: Optimising Gastric Resistance in Complex Oral Drug Products with Novel, Functional, Ready-To-Fill Capsules
Evonik showcases its novel, functional, ready-to-fill capsules portfolio, EUDRACAP
®
, explaining how its role in optimising gastric resistance in complex oral drug products.
GI/ORAL
Dr Aurelien Neveu
Granutools
POWDER CHARACTERISATION FOR PHARMACEUTICALS: BEYOND STANDARDS
Aurélien Neveu, Marco Lupo and Filip Francqui discuss the limitations of current standardised procedures for assessing the properties of pharmaceutical powders and how Granutools’ instruments – GranuPack and GranuHeap – offer a significant improvement.
GI/ORAL
Dr Aruna Railkar
Quotient Sciences
STRATEGIES FOR STREAMLINING THE DEVELOPMENT OF COMPLEX ORAL DRUG PRODUCTS
Aruna Railkar presents three case studies – one involving solubility enhancement, one modified release, and a paediatric dosage form – to illustrate the formulation challenges in complex drug programmes.
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