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OCULAR
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PREFILLED SYRINGES
CONNECTIVITY
Biocorp
PRODUCT SHOWCASE: Injay – Connected Prefilled Syringe
Biocorp presents Injay, the first prefilled syringe with built-in connectivity, providing a cost-effective and easy-to-implement solution that improves treatment adherence, upholds quality of reporting, and provides a secure treatment protocol and traceability.
EXPERT VIEW
Dr Jeffrey Philippson
THE INTERFACE BETWEEN PREFILLED SYRINGE AND AUTOINJECTOR – A DEVELOPMENT FRAMEWORK
Jeffrey Philippson and Tom Kemp outline the challenges for autoinjector developers at the interface between the device and the prefilled syringe – and describe a framework to formalise analysis of the interface.
INJECTION
Tibor Hlobik
West Pharmaceutical Services
SIMPLIFYING THE PROCESS OF DEVELOPING PREFILLED SYRINGES
Tibor Hlobik describes how the use of cyclic olefin polymer delivery systems is gaining in popularity because of the benefits they have over glass systems for complex drug applications, and explains what this advance in technology can offer drug manufacturers.
PREFILLED SYRINGES
Roland Lindner
sortimat
LED-GENERATED UV FOR ADHESIVE CURING IN MEDICAL DEVICES
Roland Lindner, Matthias Schulze and Bill Jaworski discuss how the needs around adhesive use in the manufacture of medical devices such as glass syringes have evolved and how ATS sortimat has developed a new process to meet industry demands.
INDUSTRIALISATION
Simon Strothers
3P Innovation
F2V: A STERILE, CUSTOMISABLE LIQUID FILL-FINISH PLATFORM FOR THE TOTAL LIFECYCLE
Simon Strothers presents an integrated fill-finish platform, F2V, designed to represent a commercial filling system as a bench-top solution. The article also includes a recent case study where the F2V was used by Consort Medical to help develop and industrialise a flagship delivery device.
PREFILLED SYRINGES
Tomohiro Suzuki
Mitsubishi Gas Chemical
LATEST UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE
Tomohiro Suzuki gives an update on the development of the OXYCAPT™ multilayer plastic vial and syringe – highlighting the results of recent tests comparing it with existing glass syringes.
INDUSTRIALISATION
Berthold Schopferer
Zahoransky
Z.BLIZZARD AUTOMATION SYSTEM FOR PFS: IMPROVING THE LIVES OF PATIENTS
With the ultimate objective of improving patients’ lives, Berthold Schopferer provides an overview of the company’s customer-specific automated manufacturing and assembly equipment offering for prefillable polymer syringes.
INJECTION
Marta Vilaplana
Oval Medical Technologies
FUNCTION-BASED PRIMARY PACKAGING DESIGN FOR INJECTING VISCOUS NON-NEWTONIAN FORMULATIONS
Marta Vilaplana; Alex Vasiev and Susie White explore the challenges of delivering high-viscosity, non-Newtonian fluids emphasising the importance of robust tools to characterise specific device and formulation parameters in light of increasing regulatory scrutiny.
PREFILLED SYRINGES
Aurelie Pager
BD (Becton Dickinson & Company)
8 MM NEEDLE – IMPROVING SUBCUTANEOUS CHRONIC DRUG DELIVERY
Aurelie Pager describes how reducing needle length can improve the risk profile of subcutaneous injections and can make injecting viscous formulations easier and quicker, and highlights BD’s development programme for an innovative shorter needle with ultra-thin walls for prefilled syringes.
EXPERT VIEW
Chris Franzese
Matchstick
CO-PACKAGED COMPONENTS IMPROVE PATIENT EXPERIENCE AND ENSURE CONSISTENT DRUG DELIVERY
Chris Franzese and Amy Rinaldi explore the challenges and benefits of co-packaging for manufacturers, healthcare workers and patients.
CONNECTIVITY
Chantal Wierckx
Biocorp
ADDING VALUE TO PREFILLED SYRINGES: SAFETY AND CONNECTIVITY
Chantal Wierckx and Arnaud Guillet provide an update on Newguard™, Biocorp’s integrated safety device for prefilled syringes, and explore the possible advantages connectivity can bring in the context of traceability for anti-counterfeiting, in clinical trials and in vaccination campaigns.
PREFILLED SYRINGES
Joe Reynolds
Noble
DEVELOPING DEMONSTRATORS TO INCREASE PATIENT CONFIDENCE AND REDUCE ANXIETY
Joe Reynolds discusses the value of demonstrators for making patients comfortable and effective with their prefilled syringe, leading to a significant improvement in treatment adherence and patient quality of life.
PREFILLED SYRINGES
Mr Maximilian Vogl
Gerresheimer
Gerresheimer Expands Gx RTF
®
ClearJect
®
Product Line
Maximilian Vogl describes how Gerresheimer is expanding its range of prefillable polymer syringes to include a new product: the Gx RTF
®
ClearJect
®
polymer syringe, 2.25 mL.
INDUSTRIALISATION
Berthold Schopferer
Zahoransky
Z.BLIZZARD AUTOMATION SYSTEM – IT DOESN’T GET MORE TAILOR-MADE THAN THIS
Berthold Schopferer explains how the Zahoransky’s integrated syringe manufacturing and assembly equipment allows maximum customisation and full customer involvement.
INTERVIEW
Cecile Halte
BD (Becton Dickinson & Company)
Cecile Halte, BD
In this interview, Cécile Halté, Senior Program Manager, Acute Care Segment, for BD Medical – Pharmaceutical Systems. discusses validation studies of the BD Sterifill Advance™ plastic prefilled syringe, which is intended for use in the hospital setting by healthcare professionals either for manual bolus injections, or with infusion pumps.
INDUSTRIALISATION
Michael Wiglenda
Gerresheimer
A FIVE-STEP APPROACH TO INNOVATION IN DRUG DELIVERY SYSTEMS
Michael Wiglenda explains Gerresheimer’s industrialisation offering and the five-step Gate-Model that guides its innovation process.
INTERVIEW
Dr Mircea Despa
BD (Becton Dickinson & Company)
MIRCEA DESPA & DOUG McCLURE, BD
In this interview, Dr Despa and Mr McClure discuss BD’s approach to connecting devices in its portfolio to meet patient, pharma and other stakeholder requirements. Their discussion focuses in particular on safety and security, highlighting the connected wearable injector, BD Libertas™ with Smart Option, as an example.
INJECTION
John Merhige
Credence MedSystems
TECHNOLOGY SHOWCASE: Credence MedSystems Multi-Site™ Injection System
Credence MedSystems introduces the Multi-Site™ Injection System – a product that addresses specific needs in the high-growth dermal filler market.
INJECTION
Alfred Harvey
BD (Becton Dickinson & Company)
SELECTING THE RIGHT PRIMARY CONTAINER FOR INJECTABLES IN ACUTE CARE
Alfred Harvey explains why it’s important to select the right primary container presentation – and what can happen if you get it wrong.
INJECTION
Takuya Minezaki
Mitsubishi Gas Chemical
MULTILAYER PLASTIC VIALS & SYRINGES FOR BIOLOGICS
Dr Takuya Minezaki and Tomohiro Suzuki, provide an overview of the company’s OXYCAPT™ Vials and Syringes, explaining how their multi-layered polymer material delivers the advantages of both COP and glass, and is especially suitable for biotherapeutics.
INJECTION
Berthold Schopferer
Zahoransky
NEXT-LEVEL FUTURE MANUFACTURING FOR MEDICAL TECHNOLOGY
Berthold Schopferer explains the lengths the production equipment company goes to in its efforts to ensure the customer is always king.
INJECTION
Bjarne Sørensen
Phillips-Medisize
A RE-USABLE CONNECTED AUTOINJECTOR CUSTOMISED FOR THE COMPANION
®
SAFETY SYRINGE SYSTEM
Bjarne Sørensen and John A. Merhige explore the latest developments in modular autoinjector platforms and the benefits for end users and pharmaceutical customers. They also discuss the two companies’ recent partnership for the development of a combined system that capitalises on important synergies between two compatible technologies.
PREFILLED SYRINGES
SHL Group
SOLUTIONS FOR HIGH-VOLUME DRUG DELIVERY
SHL Group introduces the high-volume variation of its Molly
®
family of products, the Molly
®
2.25, and discusses more broadly the advantages that the Molly
®
business model offers to pharmaceutical and biotech clients.
PREFILLED SYRINGES
Ingo Stephan
teamtechnik
TECHNOLOGY SHOWCASE: teamtechnik’s LED Cannula Gluing Process
Ingo Stephan introduces a new gluing process for attaching cannulas using LEDs from teamtechnik.
PREFILLED SYRINGES
Justin Schroeder
PCI Pharma Services
BIOLOGIC MEDICINES AND PATIENT-CENTRICITY – A NEW PHASE OF HOPE
Justin Schroeder discusses how the increasing biologics and biosimilars market has driven innovation and a trend towards self-administration and user-centricity in the injectable drug delivery device market.
INTERVIEW
Sagar Bejalwar
BD (Becton Dickinson & Company)
SAGAR BEJALWAR, BD MEDICAL – PHARMACEUTICAL SYSTEMS
Sagar Bejalwar discusses the product and clinician needs in delivering hyaluronic acid for cosmetic applications.
EXPERT VIEW
Marino Kriheli
HAZARDOUS DRUG HANDLING AND INVESTIGATIONAL DRUGS: LESSONS TO LEARN
Marino Kriheli discusses the need for closed-system transfer devices when handling hazardous drugs, particularly as they relate to investigational drugs, not only as key to patient and healthcare practitioner safety, but also in the context of upcoming US regulation.
PREFILLED SYRINGES
Dr Eric Chappel
Debiotech
LOW-COST DISPOSABLE WEARABLE INJECTOR PLATFORM FOR LARGE VOLUMES OF VISCOUS DRUGS
Eric Chappel, Dimitry Dumont-Fillon and Laurent-Dominique Piveteau discuss Debiotech’s novel wearable injector technology, which utilises a propellant vapour system to drive the injection, making the device both space- and cost-efficient.
EXPERT VIEW
Stuart Curtis
SIX TECHNIQUES FOR RAPID EARLY-STAGE MEDICAL DEVICE DEVELOPMENT
Stuart Curtis runs through six techniques which, in his experience, are invaluable for accelerating the early development stages of drug delivery device design and can therefore be of great use when trying to accelerate a product’s time to market.
PREFILLED SYRINGES
Hideaki Kiminami
Terumo Pharmaceutical Solutions
DEVELOPMENT OF PREFILLABLE SYRINGES TO MITIGATE THE RISK OF PARTICLE FORMATION IN BIOPHARMACEUTICALS
Hideaki Kiminami and Philippe Lauwers discuss the problem of particle formation in biopharmaceuticals packaged in prefilled syringes.
PREFILLED SYRINGES
Mindy Katz
Sorrel Medical
UV STERILISATION & THE CASE FOR PREFILLED & PRELOADED DRUG DELIVERY SYSTEMS
Mindy Katz and Ori Ben-David review the different fill form configurations of drug delivery devices, outlining the importance of the prefilled and preloaded device configuration for self-administering patients.
PREFILLED SYRINGES
Shota Arakawa
Mitsubishi Gas Chemical
MULTILAYER PLASTIC VIALS & SYRINGES FOR BIOLOGICS
Shota Arakawa and Tomohiro Suzuki discuss OXYCAPT™ Plastic Vial and Syringe, which provides a product with all the advantages of plastic, coupled with strong oxygen and UV barrier properties.
EXPERT VIEW
Lior Shtram
THE ROAD TO PREFILLED DEVICES IN NOVEL COMBINATION PRODUCTS
Lior Shtram discusses three approaches to delivering novel combination products – user-filled, user-loaded and prefilled – through the lens of sterilisation processes and requirements at the industrial manufacturing scale.
PREFILLED SYRINGES
Josh Hopkins
Noble
IMPROVING PATIENTS’ SELF-INJECTION EXPERIENCE
Jeff Lettman and Josh Hopkins explain how they worked with a client to develop a product that would function with the pre-existing drug delivery device to help rheumatoid arthritis patients with reduced dexterity.
PREFILLED SYRINGES
Janice Adkins
BD (Becton Dickinson & Company)
DRUG-DEVICE CO-PACKING SOLUTIONS TO ENHANCE DIFFERENTIATION AND IMPROVE EXPERIENCE
Janice Adkins discusses the benefits that co-packing, the practice of providing drug preparation and delivery systems along with a medication, can bring to pharmaceutical manufacturers, clinicians and patients.
EXPERT VIEW
Ursula Hahn
SAFE, CONVENIENT AND EFFICIENT: INDIVIDUALISING PREFILLED SYRINGES
Ursula Hahn discusses the value of individualised prefilled syringes and explains how small changes in design or components can make a huge difference for doctors, patients and pharmaceutical manufacturers alike.
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