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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
CONTRIBUTE
MEDIA PACK
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PULMONARY
EXPERT VIEW
Dr John N Pritchard
NEBULISERS: TIME TO REINVENT THE WHEEL
John Pritchard discusses the history of the nebuliser, its fall in popularity with the advent of DPIs and pMDIs, and its current resurgence due to the success of the mesh nebuliser, continuing on to how changing the development paradigm to utilise nebuliser technology more effectively can have significant benefits.
PULMONARY
Susana Ecenarro
INHALABLE THERAPEUTIC BIOLOGICS, A PARADIGM SHIFT FOR NON-INVASIVE EFFICIENT MEDICAL TREATMENTS
Susana Ecenarro Probst and Francesca Buttini discuss the rising prominence of biologics in the pharmaceuticals market and how dry powder inhalers utilising hard capsules are a promising potential delivery method for these new drugs.
EARLY INSIGHT
Dr Andrew K Dickerson
Fluids and Structures (FaST) Laboratory
CITRUS FRUITS INSPIRE THE NEXT GENERATION OF AIRBORNE DRUG DELIVERY
Andrew Dickerson discusses recent research undertaken by his team into the mechanics of liquid microjets created naturally by citrus fruits, and how they could be the key to a new design of drug delivery device.
INTERVIEW
Dr John Patton
Aerami Therapeutics
BILL WELCH, PHILLIPS-MEDISIZE & JOHN PATTON, DANCE BIOPHARM
In this exclusive interview with ONdrugDelivery Magazine, Bill Welch and John Patton discuss inhaled insulin, connectivity and their two companies’ close partnership
RESPIRATORY
Heli Chauhan
Proveris Scientific
REDUCING VARIABILITY IN TEST RESULTS FOR OINDPS WITH AUTOMATED ACTUATION
Heli Chauhan and Linda (Lingzhi) Liao discuss the importance of automated actuation for testing inhalation and spray devices to avoid variability introduced by manual method.
EXPERT VIEW
Dr Gunilla Petersson
PIPELINE TRENDS AND CHALLENGES IN PULMONARY DELIVERY
Gunilla Petersson provides an overview of the inhalables sector from a pharma perspective, covering the three major device types – DPIs, pMDIs and nebulisers.
PULMONARY
Mark Copley
Copley Scientific
VARIABILITY IN CASCADE IMPACTION: SOURCES, IMPACT AND STRATEGIES FOR REDUCTION
Mark Copley considers cascade impaction as a method for determining the aerodynamic particle size distribution of orally inhaled drug products, and how techniques to improve air flow control and semi-automation of the process can significantly reduce the variability involved.
PULMONARY
Pietro Pirera
IMA Group
MANUFACTURING DPIS: AN ENGINEERING PERSPECTIVE
Pietro Pirera and Stefano Crivellaro discuss the rising prominence of the DPI in inhalable drug delivery, how this has been facilitated by industrial filling technologies and how dosators in particular provide high-precision industrial-scale filling.
RESPIRATORY
Chris Vernall
Intertek Pharmaceutical Services
INTERTEK’S CENTRE OF EXCELLENCE FOR INHALED AND NASAL BIOLOGICS
Chris Vernall discusses the significance and difficulties of biologics in the inhalables sector, and how Intertek’s Centre of Excellence for Inhaled and Nasal Biologics provides valuable services for those developing products in this area.
INDUSTRIALISATION
Ameet Sule
H&T Presspart
GAS PLASMA PROCESSING: A LONG-TERM SOLUTION FOR RESPIRATORY DEVICES
Ameet Sule, Head of H&T Presspart’s Inhalation Product Technology Centre (IPCT), discusses the new challenges arising in metered dose inhaler design since the change from CFC to HFA propellants.
CONNECTIVITY
Yvonne Koehler
PARI
MONITORING NEBULISER USAGE & LUNG FUNCTION IN CLINICAL TRIALS
Carola Fuchs and Yvonne Koehler, explain how PARI’s special eTrack
®
Controller can be used to monitor adherence during inhalation therapy which facilitates objective and remote monitoring.
EXPERT VIEW
Tom Oakley
CONNECTED DRUG DELIVERY SECTOR OVERVIEW
Tom Oakley gives an overview of the state of connected devices in the drug delivery world, touching on various approaches, benefits and challenges in the sector today.
EARLY INSIGHT
Dr Kian Min Lim
PA Consulting
LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING
Kian Min Lim and David Harris discuss how tailored algorithms can accurately detect inhalers’ acoustic signatures, effectively adding connectivity without having to add a chip to the inhaler.
CONNECTIVITY
Dr Benjamin Jung
H&T Presspart
THE FUTURE OF CONNECTED ASTHMA AND COPD CARE: A STEPWISE DEVELOPMENT
Benjamin Jung outlines possible scenarios for the likely steps in the development and adoption of connected devices in the field of asthma and COPD care.
EXPERT VIEW
Bert Dekens
A POSITIVE SPIN ON DPI FORMULATION
Bert Dekens outlines some of the considerations that go into developing and processing dry powder inhaler formulations, and discusses the merits of conical high-shear mixers.
EXPERT VIEW
Dr Karlheinz Seyfang
POWDER MICRODOSING WITH 100% IN-LINE FILL WEIGHT CONTROL BY X-RAY
Karlheinz Seyfang discusses the need for filling verification in pre-metered DPI blister filling lines, going on to detail the role X-ray analysis could play in an automated verification process.
PULMONARY
Heli Chauhan
Proveris Scientific
COMPLETE SOLUTION FOR PMDI PRODUCTS: FROM DEVELOPMENT TO QUALITY CONTROL TESTING
Heli Chauhan outlines the major challenges encountered in testing pressurised metered dose inhalers, and how Proveris’ portfolio of instruments can be an invaluable addition to the testing workflow.
PULMONARY
Craig Baker
Noble
REALISTIC PULMONARY DELIVERY SYSTEM TRAINERS
Craig Baker discusses the prevalence of improper use and how addressing this issue via training devices is of benefit to manufacturers, healthcare providers and patients.
EXPERT VIEW
Mary Hutchens
THE NEW EU MEDICAL DEVICE REGULATIONS – IMPLICATIONS FOR INHALATION DEVICES
Mary Hutchens gives an overview of some of the changes wrought by last year’s introduction of the new EU Medical Device Regulation, with a specific view to its effect on inhalation devices and inhaled medical products.
EXPERT VIEW
Jamie Clayton
CHOOSING THE RIGHT DOSATOR FOR DPI DOSING
Jamie Clayton, Rajeev Dattani and Dave Seaward discuss the operation of dosators for reliable and accurate filling of DPI capsules and blisters.
EXPERT VIEW
Mark Knowles
MEETING FUTURE NEEDS FOR RESPIRATORY DRUG DELIVERY DEVELOPMENT
Mark Knowles and Collette Johnson explore the different elements that need to be considered when developing a smart inhalation drug delivery device to ensure that maximum benefit is obtained.
PULMONARY
Fernando Díez
ACG
THE SCIENCE BEHIND CAPSULE-BASED DRY POWDER INHALATION TECHNOLOGY
Here, Fernando Díez, Justin Kalafat, and Jnanadeva Bhat explain the mechanics behind cDPIs, from the scientific perspective, before looking to the future of cDPIs in the market.
EXPERT VIEW
Ryan Noble
THE LATEST DIGITAL TOOLS REVEAL ACTUAL PATIENT BEHAVIOUR
Ryan Noble and Tom Lawrie-Fussey discuss the potential of digital innovations to improve understanding of real patient behaviour and consequently increase adherence.
PULMONARY
Dr Anselm Ebert
H&T Presspart
A SIMPLE AFFORDABLE DPI: MEETING THE NEEDS OF EMERGING MARKETS
Anselm Ebert, João Ventura Fernandes, Ameet Sule and Sunita Sule discuss the rising need for respiratory medication in the developing world. They go on to highlight the novel challenges presented by these new markets and explain how a new DPI, PowdAir Plus™, meets those challenges, offering a solution to the increase in chronic respiratory conditions across the globe.
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