ONdrugDelivery - ONdrugDelivery - drug delivery industry specialised b2b information

MAKING MEDICINE EASIER TO TAKE

SPI Pharma's Graeme Macleod and Wayne Camarco discuss the rational design of excipients to meet the needs of patient-centric formulations.

FORMULATION FLEXIBILITY WITH NEW ERA HPMC CAPSULES

Sanjay Powale, Anita Solanki and Dorene Almeida discuss the benefits of HPMC capsules in overcoming challenges faced by traditional gelatin capsules.

POLYMER CHEMISTRY’S INFLUENCE ON CR TABLETS MANUFACTURED VIA DIRECT COMPRESSION

Nasrin Mahmoudi, Kevin McIntyre, Joseph Lee, Holly Bertrand, Yeli Zhang, Fernanda Onofre and Amina Faham investigate the effect of a simple direct compression method on controlled-release matrix tablet formulations.

THE FLOWABILITY OF LACTOSE POWDERS TO OPTIMISE TABLETING PROCESSES

Dr Aurelien Neveu

THE FLOWABILITY OF LACTOSE POWDERS TO OPTIMISE TABLETING PROCESSES

Aurélien Neveu, Pauline Janssen and Geoffroy Lumay discuss how new measurement methods can help gain a better understanding of the flowability of lactose powders – a necessary step for future improvement of oral delivery systems.

NANOPARTICLE ENGINEERING: REVOLUTIONISING ORAL DRUG DEVELOPMENT & DELIVERY

NANOPARTICLE ENGINEERING: REVOLUTIONISING ORAL DRUG DEVELOPMENT & DELIVERY

Satu Lakio and Niklas Sandler discuss the benefits of nanoparticle engineering technology as a means of improving the bioavailability and solubility of drug compounds.

TECHNOLOGY SHOWCASE: Röchling Medical’s Sympfiny<sup>®</sup>

Röchling Medical

TECHNOLOGY SHOWCASE: Röchling Medical’s Sympfiny^®

Röchling Medical presents Sympfiny®, an innovative system for dosing and delivering multiparticulate, dry powder, and microsphere drug formulations for oral delivery, which it developed In collaboration with HS Design.

AN EASY PILL TO SWALLOW

AN EASY PILL TO SWALLOW

Kelly Boyer and Ali Rajabi-Siahboomi explore the role of different tablet coating materials in improving the patient experience and adherence to prescription regimens.

INTERVIEW WITH MARIA FLYNN, ADARE PHARMACEUTICALS

Adare Pharmaceuticals

INTERVIEW WITH MARIA FLYNN, ADARE PHARMACEUTICALS

Adare Pharma's Maria Flynn talks with ONdrugDelivery about trends in the oral drug development and delivery space, completing the Orbis Biosciences acquisition during a global pandemic, and how the excellent technology portfolio and strategic fit between Orbis and Adare form part of the combined organisation’s unique story.

INNOVATIONS IN 3D PRINTED PHARMACEUTICALS

Sarah Trenfield

INNOVATIONS IN 3D PRINTED PHARMACEUTICALS

Sarah Trenfield, Abdul Basit and Alvaro Goyanes discuss the latest innovations in 3D printed pharmaceuticals.

RECENT DEVELOPMENT IN COMPLEX TABLET FORMULATION DESIGN FOR VERSATILE APPLICATIONS

Dr Mathieu Degomme

Skyepharma Production

RECENT DEVELOPMENT IN COMPLEX TABLET FORMULATION DESIGN FOR VERSATILE APPLICATIONS

Mathieu Degomme and Aline Moulin outline three case studies from recent early-stage development programmes to illustrate what kind of complex tablets can be developed to meet specific target dissolution profiles for versatile applications.

THE RISE OF COMPLEX ORAL DELIVERY SYSTEMS

María Fernández-Martos Balson

THE RISE OF COMPLEX ORAL DELIVERY SYSTEMS

María Fernández-Martos Balson and Bastiaan De Leeuw explore the oral delivery of biologics and the challenges that must be overcome in order to enhance bioavailability. The authors also take a look at some recently developed drug-device combinations.

OPTICORE™: A FIRST-IN-CLASS COLONIC TARGETING TECHNOLOGY

Dr Felipe Varum

Tillotts Pharma

OPTICORE™: A FIRST-IN-CLASS COLONIC TARGETING TECHNOLOGY

Felipe Varum, Roberto Bravo and Abdul Basit discuss the use of colonic targeting coating technology OPTICORE™ to deliver APIs in the treatment of ulcerative colitis (UC) patients.

INTERVIEW WITH MILENA BATALLA, PHD, PANARUM

INTERVIEW WITH MILENA BATALLA, PHD, PANARUM

Dr Batalla introduces the company and describes its Proteoral^® technology for the oral delivery of proteins to the bloodstream, therapeutic applications, and products to date. Panarum is an Argentine company and this interview is presented here in Spanish and English, an exciting first for ONdrugDelivery!

UNIQUE MINITABLET DISPENSER MEETS FLEXIBLE ORAL DOSING NEED

Bjørn Knud Andersen

Phillips-Medisize

UNIQUE MINITABLET DISPENSER MEETS FLEXIBLE ORAL DOSING NEED

Bjørn Knud Andersen discusses how an innovative minitablet dispenser that mounts on a standard medication container simply and effectively meets the growing needs of patients in paediatrics, geriatrics, oncology and other areas who require reliable customised oral dosing.

COVID-19: A CATALYST FOR IMPLEMENTING CONNECTED HEALTHCARE PRODUCTS?

Napoleon Monroe

COVID-19: A CATALYST FOR IMPLEMENTING CONNECTED HEALTHCARE PRODUCTS?

Napoleon Monroe analyses how COVID-19 is catalysing a wide range of reactions in healthcare, explaining how drug and device connectivity are essential to improving patient access to treatment – and patient outcomes – as well as reducing overall cost.

THE AWARD-WINNING CREDENCE CONNECT™ AUTO-SENSING INJECTION SYSTEM

Credence MedSystems

THE AWARD-WINNING CREDENCE CONNECT™ AUTO-SENSING INJECTION SYSTEM

John Merhige explains how connectivity that is universally applicable to any existing prefilled syringe platform adds value throughout the ecosystem, both including and beyond the “compliance business model”.

POLYMERIC EMI SHIELDING: PROVIDING A MORE SECURE FUTURE FOR PATIENTS

POLYMERIC EMI SHIELDING: PROVIDING A MORE SECURE FUTURE FOR PATIENTS

Marnik Vaes, Leen-Pieter Deurloo and Martin Sas discuss the role of polymeric electromagnetic interference shielding in providing a more secure future for patients in a connected world.

SENSORS ARE TOOLS – BUT HOW DO YOU MAKE THEM SMART?

SENSORS ARE TOOLS – BUT HOW DO YOU MAKE THEM SMART?

Gaël Senée and Arnaud Guillet explore the benefits of Mallya – a smart sensor that turns conventional injection pens into connected devices. They also discuss the crucial role Biocorp’s connected prefilled syringe, Injay, could play in future COVID-19 vaccination programmes.

RISKS AND REAL-WORLD SOLUTIONS FOR CONNECTED MEDICAL DEVICES

RISKS AND REAL-WORLD SOLUTIONS FOR CONNECTED MEDICAL DEVICES

Tom Oakley discusses the risks surrounding the use of connected drug delivery devices – and the real-world solutions that have either been proved or are being trialled.

APPLYING CONNECTIVITY TO ENHANCE THE TRAINING STANDARD OF CARE FOR SELF-INJECTION

APPLYING CONNECTIVITY TO ENHANCE THE TRAINING STANDARD OF CARE FOR SELF-INJECTION

Erin Miller looks at how connectivity can be used to enhance training to help address the challenges of accuracy and non-adherence when patients self-inject their medications.

INTERVIEW WITH SAI SHANKAR, ADAM SHAIN & MARCUS BATES

INTERVIEW WITH SAI SHANKAR, ADAM SHAIN & MARCUS BATES

Sai Shankar, Adam Shain and Marcus Bates discuss the full potential of connectivity, coronavirus as a potential accelerator of adoption, and the place of connected drug delivery systems within Aptar Pharma’s broader offering to industry.

MEETING THE CHALLENGES OF COVID-19

Beo Arana de Martinez

E3D – Elcam Drug Delivery Devices

MEETING THE CHALLENGES OF COVID-19

Beo Arana de Martinez and Ilan Shopen discuss the effects of the COVID-19 pandemic on patient populations, how the healthcare industry has intensified activity to fight the virus, and how connected devices that facilitate self-injection and remote monitoring are coming into their own.

CONNECTED DEVICE DATA NEEDED TO MAKE HOME CARE THE STANDARD

Dr Andrei Yosef

CONNECTED DEVICE DATA NEEDED TO MAKE HOME CARE THE STANDARD

With home care on the increase as a result of the coronavirus pandemic, Andrei Yosef looks at the crucial role played by connected home care medical devices and the data they generate.

EPIWATCH: A NOVEL LIFE-SAVING MICRO AUTOINJECTOR IN A SMART WATCH

EPIWATCH: A NOVEL LIFE-SAVING MICRO AUTOINJECTOR IN A SMART WATCH

Amber Witteman, Thijs Roebers and Dirk-Jan Opstelten introduce the company’s patented innovation, a wearable autoinjector customised to fit the wrist.

Adding value to Drug Delivery with Connectivity

Phillips-Medisize

Adding value to Drug Delivery with Connectivity

In this video presentation, Kevin Deane looks at how connectivity applied in drug delivery technologies can provide better solutions for patients and for industry and add value for all stakeholders.

Chalmers University Pilot Project Developing Nasal spray to deliver vaccine against COVID-19

Chalmers University Pilot Project Developing Nasal spray to deliver vaccine against COVID-19

A unique concept for a nasal spray mRNA vaccine against COVID-19 is being investigated in a new pilot project. The Swedish group is exploring design principles for nasal immunisation, developing a biomimetic nanoparticle provided with both immune enhancers and a targeting protein.

ESTABLISHING DATA-DRIVEN DESIGN AND MANUFACTURING FOR MEDICAL DEVICES

Frederick Gertz

ESTABLISHING DATA-DRIVEN DESIGN AND MANUFACTURING FOR MEDICAL DEVICES

Frederick Gertz explores the benefits for medical device design and manufacturing organisations of adapting to the use of big data and analytics.

INTERVIEW WITH STEVEN KAUFMAN, STEVANATO & URI BARUCH, CDP

Stevanato Group

INTERVIEW WITH STEVEN KAUFMAN, STEVANATO & URI BARUCH, CDP

Steven Kaufman and Uri Baruch discuss the recently announced collaboration between their two companies to accelerate the development of a new variable-dose, cartridge-based pen injector platform for diabetes.

A NOVEL PREFILLABLE SYRINGE WITH A GLASS PRIMARY CONTAINER BUT NO NEED FOR EXTREME THERMAL REFORMING

PREFILLED SYRINGES

Dr Stephen Shue

SaferMed Technologies

A NOVEL PREFILLABLE SYRINGE WITH A GLASS PRIMARY CONTAINER BUT NO NEED FOR EXTREME THERMAL REFORMING

Stephen Shue introduces a proprietary prefillable syringe, the SMPFS, whose novel glass-tube-plus-plastic-sheath design enables the use of a standard glass tube primary drug container, but avoids the need for the extreme thermal reforming process that conventional glass prefillable syringes must undergo.

UPDATE ON OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE

PREFILLED SYRINGES

Tomohiro Suzuki

Mitsubishi Gas Chemical

UPDATE ON OXYCAPT MULTILAYER PLASTIC VIAL AND SYRINGE

Tomohiro Suzuki gives an update, including new oxygen barrier data, on the development of the OXYCAPT™ multilayer plastic vial and syringe.

Shorter Needles with Thinner Walls to Improve Injection Experience in Chronic Care

PREFILLED SYRINGES

BD (Becton Dickinson & Company)

Shorter Needles with Thinner Walls to Improve Injection Experience in Chronic Care

Aurélie Pager, Brigitte Duinat and Barbara Alves look at how new BD Neopak™ XtraFlow™ prefillable syringes with shorter, 8 mm needles and thinner-wall cannula technology are set to improve the injection experience for subcutaneous drug delivery in chronic care.

WHICH IS THE BETTER TOXICITY TESTING STRATEGY FOR COMBINATION DEVICES?

WHICH IS THE BETTER TOXICITY TESTING STRATEGY FOR COMBINATION DEVICES?

Mark Turner explores the issue of toxicity testing for combination devices and asks which is the better testing strategy – ISO 10993 or extractables and leachables?

DESIGN CONSIDERATIONS FOR IMPROVING TRAINING DEVICE SAFETY AND EFFECTIVENESS

DESIGN CONSIDERATIONS FOR IMPROVING TRAINING DEVICE SAFETY AND EFFECTIVENESS

Yvonne Limpens and Brenda van Geel, explore the design considerations that need to be taken into account when developing training devices that are safe and effective – and support patients in learning how to administer an injection correctly.

THE NEXT GENERATION OF COATED PLUNGERS

Carina Van Eester

THE NEXT GENERATION OF COATED PLUNGERS

Carina Van Eester explores the benefits of fully coated plungers for prefilled syringes and cartridges.

APPLICATION OF CFD IN THE DEVELOPMENT OF A WEARABLE BOLUS INJECTOR

Validus Engineering

APPLICATION OF CFD IN THE DEVELOPMENT OF A WEARABLE BOLUS INJECTOR

Marcus Hall, Björn Ullbrand and Claus Schmidt Møller describe the use of computational fluid dynamics (CFD) as the primary design and analysis tool in the development of a wearable bolus injector.

EU MDR DEADLINE DELAY: WHAT DOES IT MEAN FOR THE MEDICAL DEVICE INDUSTRY?

EU MDR DEADLINE DELAY: WHAT DOES IT MEAN FOR THE MEDICAL DEVICE INDUSTRY?

With the compliance deadline for the EU Medical Device Regulation recently delayed by a year due to the novel coronavirus pandemic, Beth Crandall looks at what it means for the medical device industry.

SILICA RE-EMERGES AS POTENTIAL NUCLEIC ACID DELIVERY VECTOR

SILICA RE-EMERGES AS POTENTIAL NUCLEIC ACID DELIVERY VECTOR

Nigel Theobald looks at the challenges of oligonucleotide delivery and explores approaches to overcome them.

Senzer to Create Targeted Inhaled Antivirals for COVID-19

Senzer to Create Targeted Inhaled Antivirals for COVID-19

Senzer Pharmaceuticals has launched a Critical Care Division, which will utilise its expertise in respiratory pharmaceuticals to create targeted antiviral treatments for COVID-19.

Covis Pharma’s Alvesco (ciclesonide) Inhaler Enters Phase III COVID-19 Trials

Covis Pharma’s Alvesco (ciclesonide) Inhaler Enters Phase III COVID-19 Trials

Covis Pharma's inhaled glucocorticoid, Alvesco (ciclesonide), has entered a US multicentre, randomised, double-blind, placebo-controlled Phase III safety and efficacy trial in 400 non-hospitalised patients 12 years of age and older with symptomatic COVID-19. The product is delivered twice daily via a pMDI.

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Li-Chun Tsou, PhD, MBA
Principal Engineer
Merck & Co

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Plan Strategic

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