ONdrugDelivery - ONdrugDelivery - drug delivery industry specialised b2b information

CREATING TIMELESS DEVICE TECHNOLOGIES

SHL Medical's Andrew Moore and Gene Rhode Fuensalida Pantig discuss the importance of a sound strategy for product lifecycle management.

KEY CONSIDERATIONS FOR AN OPTIMAL EMERGENCY-USE AUTOINJECTOR

Adam Stops and William Fortina Maverick introduce Maverick, an emergency-use autoinjector, and discuss key considerations during the device design and development, for primary packaging and manufacturing and assembly.

AIDAPTUS^®: OWEN MUMFORD INTRODUCES ITS NEXT-GENERATION PLATFORM AUTOINJECTOR

Michael Earl introduces the next-generation Aidaptus^® autoinjector, explaining how this latest platform device from Owen Mumford can contribute to a faster speed-to-market, increased flexibility during drug development and improved patient outcomes.

INTERVIEW WITH MATHIAS ROMACKER, EX-PFIZER, INJECTION DEVICES STRATEGY CONSULTANT

Mathias Romacker

INTERVIEW WITH MATHIAS ROMACKER, EX-PFIZER, INJECTION DEVICES STRATEGY CONSULTANT

In this exclusive interview, Mathias Romacker discusses a broad range of topics, from his professional expertise and history seeing the parenteral sector evolve first-hand, to his personal experience as a Crohn’s disease patient making use of the very devices he’s seen grow and develop.

RELENTLESS PRECISION DELIVERS VALUE IN NEEDLE-HANDLING AUTOMATION FOR COMBINATION PRODUCTS

INDUSTRIALISATION

William Jaworski

Mikron Automation

RELENTLESS PRECISION DELIVERS VALUE IN NEEDLE-HANDLING AUTOMATION FOR COMBINATION PRODUCTS

William Jaworski and Michael Gunner discuss the precision and complex manipulation of needles required for the latest combination medical products.

FULLY AUTOMATED ASSEMBLY AND FUNCTIONAL TESTING FOR PEN INJECTORS AND AUTOINJECTORS

Carsten Köhler

FULLY AUTOMATED ASSEMBLY AND FUNCTIONAL TESTING FOR PEN INJECTORS AND AUTOINJECTORS

Carsten Köhler, Umit Ismail Tsavous and Gerd Vosshage explain the company’s processes for the automated assembly and testing of pen and autoinjectors.

CHALLENGES IN HIGH-VISCOSITY, HIGH-VOLUME DRUG DELIVERY

CHALLENGES IN HIGH-VISCOSITY, HIGH-VOLUME DRUG DELIVERY

Michael Roe discusses the development of the Aerio™ Platform of gas-powered injection systems.

THREE PHASES TO SUCCESS IN STERILE INJECTABLES TECHNOLOGY TRANSFER

Pfizer CentreOne

THREE PHASES TO SUCCESS IN STERILE INJECTABLES TECHNOLOGY TRANSFER

Jennifer Quint offers insights into how to plan and execute technology transfer effectively, explaining Pfizer CentreOne’s three-phased approach that can successfully support this pivotal event in a drug product programme’s journey to commercialisation.

PRODUCT SHOWCASE: ZwickRoell – Comprehensive Automated Testing Solutions

INDUSTRIALISATION

Wolfgang Moersch

PRODUCT SHOWCASE: ZwickRoell – Comprehensive Automated Testing Solutions

ZwickRoell showcases its comprehensive automated testing solutions.

UNDERSTANDING YOUR PROCESS RELIABILITY: COMPLIANCE CONSIDERATIONS FOR EMERGENCY-USE DELIVERY SYSTEMS

UNDERSTANDING YOUR PROCESS RELIABILITY: COMPLIANCE CONSIDERATIONS FOR EMERGENCY-USE DELIVERY SYSTEMS

Richard Motruk and Nathan Blazei discuss the issues to be considered in light of the US FDA’s tightened reliability standards for emergency-use autoinjectors.

HERE TODAY AND DEFINITELY NOT GONE TOMORROW: WHY SIMPLICITY AND EASE OF USE ARE THE KEY FOR A NEW GENERATION OF REUSABLE INJECTORS

Dr Kate Hudson-Farmer

Phillips-Medisize

HERE TODAY AND DEFINITELY NOT GONE TOMORROW: WHY SIMPLICITY AND EASE OF USE ARE THE KEY FOR A NEW GENERATION OF REUSABLE INJECTORS

Kate Hudson-Farmer discusses how a new electronic reusable autoinjector – the Aria Smart Autoinjector from Phillips-Medisize – has been designed and user-tested to challenge the preconceived ease-of-use notions about electronic autoinjectors, in addition to addressing how macro trends and personal consumer subtleties could become increasingly important in creating a competitive position as devices seek to improve patient engagement.

GX INNOSAFE – GREATER PROTECTION AGAINST NEEDLESTICK INJURIES

PREFILLED SYRINGES

Dr Wenzel Novak

GX INNOSAFE – GREATER PROTECTION AGAINST NEEDLESTICK INJURIES

Wenzel Novak and Stefan Verheyden introduce Gx InnoSafe, a novel integrated passive needle safety system for preventing needlestick injuries and accidental reuse of syringes that minimises additional burden on healthcare workers during injection and can be integrated into existing pharmaceutical filling operations without the need for adaptation or conversion of processing lines.

A NEW MINDSET FOR COMBINATION PRODUCT DEVELOPMENT

Asmita Khanolkar

A NEW MINDSET FOR COMBINATION PRODUCT DEVELOPMENT

Asmita Khanolkar outlines the latest trends in combination product development to overcome some of the current challenges of high dose/viscosity/volume delivery.

INTERVIEW WITH STEPHEN M PERRY AND NICHOLAS CICCARELLI

INTERVIEW WITH STEPHEN M PERRY AND NICHOLAS CICCARELLI

Stephen Perry and Nicholas Ciccarelli discuss the August 2021 acquisition of Neuma by Kymanox, highlighting how the acquisition has positioned Kymanox to lead the development of particularly complex drug delivery systems and cutting-edge medical device technologies, providing additional services to progress combination products to market.

PHOTOSTABILITY TESTS OF ANTIBODY DRUGS

PREFILLED SYRINGES

Mitsubishi Gas Chemical

PHOTOSTABILITY TESTS OF ANTIBODY DRUGS

Yoshiko Sakuma and Tomohiro Suzuki provide an overview of Mitsubishi Gas Chemical's OXYCAPT multilayer vial and syringe, with a particular focus on the recent investigations into the interaction of OXYCAPT’s UV barrier with the photostability of antibody drugs, compared with standard cyclo-olefin polymer and Type 1 glass.

YPSODOSE – SIMPLIFYING LARGE-VOLUME PATCH INJECTIONS

YPSODOSE – SIMPLIFYING LARGE-VOLUME PATCH INJECTIONS

Ian Thompson provides the latest insights into the YpsoDose prefilled and pre-assembled patch injector as it moves into the industrialisation phase for clinical trials.

DESIGNING DRUG DELIVERY DEVICES THROUGH COLLABORATIVE USABILITY TESTING

DESIGNING DRUG DELIVERY DEVICES THROUGH COLLABORATIVE USABILITY TESTING

Alice Bogrash examines how the company uses human factors studies to design drug delivery devices that respond to user needs, while providing a competitive advantage for pharmaceutical companies looking to introduce innovative combination products to the market.

MEETING EMERGING STAKEHOLDER NEEDS WITH THE SUBCUJECT WEARABLE BOLUS INJECTOR

Phillips-Medisize

MEETING EMERGING STAKEHOLDER NEEDS WITH THE SUBCUJECT WEARABLE BOLUS INJECTOR

Tony Bedford looks at the emerging market for on-body injectors coupled with stakeholder needs and introduces the Subcuject wearable bolus injector, which is designed to accommodate these requirements.

TACKLING HIGH-VOLUME ADMINISTRATION CHALLENGES WITH A SMART, SUSTAINABLE ON-BODY INJECTOR PLATFORM

Séverine Duband

TACKLING HIGH-VOLUME ADMINISTRATION CHALLENGES WITH A SMART, SUSTAINABLE ON-BODY INJECTOR PLATFORM

Séverine Duband introduces Symbioze, Nemera’s novel on-body injector platform device, comprising a reusable main unit and disposable prefilled drug container, and offering a balance between the need to deliver advanced formulations at high volumes and the desire for patient-centric ease-of-use that enables patients to self-administer their therapies at home.

HIGH PRECISION IN PLASTICS IMPROVES THE QUALITY OF LIFE OF DIABETES PATIENTS

Weidmann Medical Technology

HIGH PRECISION IN PLASTICS IMPROVES THE QUALITY OF LIFE OF DIABETES PATIENTS

Steffen Reuter discusses the importance of high precision when manufacturing injection moulded components for wearable insulin delivery devices, with particular reference to three such parts from a recent project as a case study for Weidmann Medical Technology’s approach.

USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN

USING SIMULATION AND MODELLING VERSUS PROTOTYPING FOR MEDICAL RADIO FREQUENCY DESIGN

Enrico Denna looks at the advantages of a simulation and modelling approach over prototyping for the design of medical products.

COMPLEXITY OF PATCH PUMP ASSEMBLY AND CONSIDERATIONS FOR MASTERING IT

COMPLEXITY OF PATCH PUMP ASSEMBLY AND CONSIDERATIONS FOR MASTERING IT

Roger Nordy discusses the complexities of patch pump assembly and explains how ATS has been mastering the intricacies of the automation process to take on the growing industry demand.

VECTRA<sup>®</sup> MT<sup>®</sup> LCP BRINGS THE ADVANTAGES OF LIQUID CRYSTAL POLYMERS TO WEARABLE INJECTORS

VECTRA^® MT^® LCP BRINGS THE ADVANTAGES OF LIQUID CRYSTAL POLYMERS TO WEARABLE INJECTORS

Wim Vos, Dave Pellegrino and Rob Haley discuss the myriad benefits of Vectra^® MT^® LCP, Celanese’s medical-grade liquid crystal polymer, for wearable injection devices, including improved patient comfort, greater design flexibility and reduced processing costs.

REPOSITIONING FROM IV TO VIAL-BASED SC FOR LARGE-VOLUME BIOLOGICS

REPOSITIONING FROM IV TO VIAL-BASED SC FOR LARGE-VOLUME BIOLOGICS

Tom Mayer discusses the growing trend of moving away from intravenous drugs administered in clinical and hospital settings to at-home, self-administered vial-based subcutaneous delivery for cost savings, better lifecycle management and improved care.

OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES

OPTIONS FOR ACTIVATION OF BATTERY-OPERATED MEDICAL DEVICES

Tim Resker looks at new technologies for powering on battery-operated drug delivery devices while considering battery drain, ingress protection and user-friendliness.

DRUG DELIVERY: WHAT DO PATIENTS AND PROVIDERS WANT?

Matthew Huddleston

Enable Injections

DRUG DELIVERY: WHAT DO PATIENTS AND PROVIDERS WANT?

Matthew Huddleston and Jennifer Estep discuss current drug delivery options and the value of convenient care.

CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS

Marcus Jarman-Smith

CONNECTED DEVICES CHALLENGE: HOW TO DEVELOP CONCEPT DEVICES WITH PEEK POLYMERS

Marcus Jarman-Smith, Adam Salmen, John Devine, Ernst Hupkes and Dennis Freie discuss the value of PEEK, a high-performance polymer, in drug delivery device design, using two concept devices – an on-body patch pump and vaporiser inhaler.

The Secrets of Solubility Enhancement Success with EUDRAGIT<sup>®</sup> Carriers

Dr Jessica Mueller-Albers

The Secrets of Solubility Enhancement Success with EUDRAGIT^® Carriers

Jessica Mueller-Albers discusses how Evonik’s EUDRAGIT^® functional polymers can enhance drug solubility and permeability, with a focus on carriers, screening tools and manufacturing processes.

ARE VIRTUAL EVENTS A SUITABLE REPLACEMENT FOR FACE-TO-FACE EQUIVALENTS POST-PANDEMIC?

Mr Denis Marteau

ARE VIRTUAL EVENTS A SUITABLE REPLACEMENT FOR FACE-TO-FACE EQUIVALENTS POST-PANDEMIC?

Denis Marteau looks at the future of virtual industry events and conferences in a post-pandemic future.

DEVELOPING A FULLY AUTOMATED MODULAR MACHINE PLATFORM FOR AUTOINJECTOR TESTING

INDUSTRIALISATION

DEVELOPING A FULLY AUTOMATED MODULAR MACHINE PLATFORM FOR AUTOINJECTOR TESTING

Lucy Chung and Gilbert Fluetsch discuss the benefits of a modular automated test platform.

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Dr Antonio Costa

ENHANCED PROCESS CONTROL FOR LIPID-BASED NANOPARTICLES: LNPS AND LIPOSOMES

Antonio Costa discusses the use of lipid nanoparticles in the modern drug delivery industry and introduces the DIANT system for the continuous processing of nanoparticles with integrated process analytical technology, which can provide the quality required for these injectable, complex formulations.

THE FUTURE OF CONTAINER-LEVEL TRACEABILITY FOR PREFILLABLE SYRINGES

INDUSTRIALISATION

BD (Becton Dickinson & Company)

THE FUTURE OF CONTAINER-LEVEL TRACEABILITY FOR PREFILLABLE SYRINGES

Sam Eubanks and Hervé Soukiassian discuss the BD traceability solution. This concept under development aims to deliver traceability at the unique container level from manufacture to the point of care.

INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING

INDUSTRIALISATION

Napoleon Monroe

New Directions Technology Consulting

INDUSTRIALISATION OF DRUG DELIVERY BEYOND MANUFACTURING

Napoleon Monroe considers the impact of the changing technological landscape on how industrialisation in the healthcare industry is evolving, with reference to the idea of “patients as consumers” and how the relationship between consumers, information and industry has evolved in other sectors, such as tech and retail – and how big players in those sectors are looking to move into and disrupt healthcare.

UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

INDUSTRIALISATION

Hiroki Hasegawa

Mitsubishi Gas Chemical

UPDATE ON OXYCAPT™ MULTILAYER PLASTIC VIAL AND SYRINGE

Hiroki Hasegawa and Tomohiro Suzuki discuss the advantages of OXYCAPT™ multilayer plastic vial and syringe, which combine the benefits of cyclo-olefin polymer with excellent oxygen and UV barrier properties. In particular, the authors focus on recent studies that highlight OXYCAPT’s very low levels of extractables.

THE FOURTH INDUSTRIAL REVOLUTION – ROBOTICS AND THE LABORATORY

INDUSTRIALISATION

Prof Marc Brown

THE FOURTH INDUSTRIAL REVOLUTION – ROBOTICS AND THE LABORATORY

Marc Brown and Jon Lenn look at MedPharm’s implementation of automated robotic systems in enhancing workflow and the company’s plans for the future implementation of robotics in formulation development.

AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE

AUTOMATED LIPID NANOPARTICLE PRODUCTION: FROM PROTOCOL DEVELOPMENT TO GMP MANUFACTURE

Richard Gray and Julia Rashba-Step discuss the benefits of automated lipid nanoparticle production.

OVERCOMING DEVELOPMENT OBSTACLES TO THE DELIVERY OF EFFECTIVE OCULAR THERAPY

OVERCOMING DEVELOPMENT OBSTACLES TO THE DELIVERY OF EFFECTIVE OCULAR THERAPY

Robert Lee discusses the growth of the ocular drug delivery market, the challenges formulators face in developing novel ocular technologies, and the role contract development and manufacturing organisations have to play in this growing market segment.

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Mr Richard Joye

SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY

Richard Joye and Tim Morch discuss the advantages of using dissolvable microneedles for the delivery of vaccines, particularly in regards to storage and transport, and introduce SeriTech’s fast-detaching dissolvable microneedle technology.

REMOVING CLINICAL TRIAL BIAS WITH OVER-ENCAPSULATION

Frédérique Bordes-Picard

REMOVING CLINICAL TRIAL BIAS WITH OVER-ENCAPSULATION

Frédérique Bordes-Picard, Julien Lamps and Stephen Rode discuss the considerations to take into account when using over-encapsulation to blind clinical trials, including the advantages of hydroxypropyl methylcellulose over gelatin as a material.

1
2
3
…
27
Next

See what ondrugdelivery's readers and contributors think

Donna Bibber
President
Micro Engineering Solutions

I picked up your latest copy at the Boston PODD event and read it with great interest. You’ve really come a long way and you put out an amazingly professional and value-packed magazine.

Li-Chun Tsou, PhD, MBA
Principal Engineer
Merck & Co

Your website and publication is a great asset for me. I’d recommend your publication to my colleagues. I am sure that we will gain knowledge and update information through your timely report. Thanks for making it available.

Dr Cristian Vilos

I‘m working on the development of microparticles for the release of veterinary antibiotics, and polymeric nanoparticles for siRNA and chemotherapeutic delivery. ONdrugDelivery has been a very usefull platform to connect the scientific research, and marketed drug development.

Matt Kempton
Snr Project Engineer
Corning Incorporated

I am extremely impressed with the comprehensive presentation of information and problem/solution points detailed ... Kudos to you for an extremely well written article with succinct and robust scientific body of knowledge.

Top