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INDUSTRIALISATION
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
MORE
INTERVIEWS
EXPERT VIEWS
EARLY INSIGHTS
COMPANY LISTINGS
OUR AUTHORS
THE MAGAZINE
EVENTS
ED CALENDAR
CONTRIBUTE
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SKIN
MICRONEEDLES
DELIVERABILITY, ACCEPTABILITY, AVAILABILITY: ASSESSING THE EVOLVING STRENGTHS OF MICRONEEDLE-BASED DRUG DELIVERY
Dr May Pidding explores the growth and future potential of microneedle technology and its suitability for a broad range of drug delivery applications, specifically presenting the case for the accelerated uptake and wider adoption of Microneedle Array Patch (MAP) technology.
EXPERT VIEW
TRANSDERMAL DRUG DELIVERY: ENHANCING PERMEABILITY AND IN VIVO TRANSLATION
Dr Leo Pan provides insights into the field of transdermal drug delivery and investigates the two primary approaches being taken to advance the sector – enhancing the ability of drugs to permeate through the skin barrier and translating in vitro data to an in vivo reality.
SKIN
Dr Nicky Bertollo
Pharma Latch
IT’S TIME TO CONSIDER INTRADERMAL DELIVERY
Nicky Bertollo, Adam Rock and Saidhbh O’Callaghan discuss the progress Pharma Latch’s intradermal drug delivery platform is making towards realising the potential the intradermal route offers to drug developers, especially for vaccines.
EARLY INSIGHT
Dr Nicky Bertollo
Pharma Latch
HOW DO YOU PERCEIVE INTRADERMAL DELIVERY? THINK AGAIN…
Nicky Bertollo, Adam Rock and Ronan Byrne discuss the benefits and limitations of intradermal delivery – and introduce the Pharma Latch Hollow intradermal injection device.
SKIN
Dr Marie-Christine Klein
URSATEC
“PRESERVATIVE FREE” – THE SKIN MICROBIOME’S CLOSE FRIEND
Marie-Christine Klein, Andreas Bilstein and Julia Krüger discuss the effects of preservatives on the skin microbiome and consider new technologies that minimise the percentage of preserving agents used in cosmetic formulations.
INTERVIEW
Dr Stefan Hellbardt
Aptar Pharma
DE-RISKING COMBINATION PRODUCT REGISTRATION FOR SEMI-SOLIDS WITH APTAR PHARMA’S AIRLESS
+
SYSTEM – AN INTERVIEW WITH STEFAN HELLBARDT
Stefan Hellbardt discusses the increasing demand for airless systems in the dermal drug delivery market, the advantages of these systems and Aptar Pharma’s own offering in this space, including its Airless+ packaging system and Extended Support services.
MICRONEEDLES
Bart van Oorschot
uPATCH
UNLOCKING THE POTENTIAL OF MICRONEEDLE TECHNOLOGY
Bart van Oorschot and Maarten Smit discuss the exciting potential of microneedle-based delivery systems to transform the drug delivery industry, the challenges faced by this technology and how the use of an applicator may be the way to overcome them.
EARLY INSIGHT
Alina Su
NovaXS Biotech
SAY “NO MORE” TO NEEDLES: NEEDLE-FREE SELF-INJECTION TECHNOLOGY FOR PAINLESS, BETTER CARE
Alina Su discusses the need for improved and optimised remote healthcare to meet current challenges in the industry, and introduces Telosis, the company’s patent-pending connected needle-free injection device that is poised to provide answers to these challenges.
EXPERT VIEW
Dr Gabriel Villar
THE NEXT GENERATION OF MICRONEEDLES: HARNESSING A BILLION YEARS OF EVOLUTION
Gabriel Villar and Ethan Miller consider examples of nature’s solutions to four challenges faced by microneedles for drug delivery. For each challenge, the authors explain how a natural organism has tackled it and what lessons may be directly applied to microneedle design.
SKIN
Dr Claire Authesserre
Eveon
AN AIRLESS SPRAY NOZZLE TO PRODUCE A FINE AND SOFT MIST
Claire Authesserre and Florian Corne discuss the current challenges faced by the topical spray-based delivery of therapeutics and how EVEON’s Ad-Mist™ spray nozzle overcomes these challenges to harness the potential of this delivery route.
EARLY INSIGHT
Dr Dimitrios Lamprou
Queen's University Belfast
3D-PRINTED HOLLOW MICRONEEDLES: A NEW FRONTIER FOR TRANSDERMAL DRUG DELIVERY
Dimitrios Lamprou and Essyrose Mathew discuss the potential of 3D-printed hollow microneedles for transdermal drug delivery.
SKIN
Daryl Bassett
Excipient Choices and Why They Matter in Topical Formulations
Daryl Bassett and David Barnes show how the choice of common excipients can have a material impact on manufacturing success, quality and, ultimately, commercial success for topical formulations, which generally require the incorporation of more excipients than other products to deliver their API payload effectively.
SUSTAINABILITY
Julien Storz
Aptar Pharma
SUCCESSFULLY BALANCING THE NEEDS OF THE PLANET WITH THE NEEDS OF THE PATIENT
Christophe Marie, Taylor Price and Julien Storz chart the commitments and progress made to date by Aptar in achieving its sustainability targets. The authors also provide examples of integrated, circular economy initiatives undertaken by Aptar Pharma at a product solution level and comment on concrete commitments that can be made to further progress towards sustainability.
EXPERT VIEW
Kay Sinclair
EIGHT ESSENTIAL SUSTAINABILITY TERMS FOR THE MEDICAL DEVICE INDUSTRY
Kay Sinclair, Brennan Miles and Charlie Dean provide an overview of eight terms key to a common understanding in the ongoing, and crucial, discussion surrounding sustainability.
INDUSTRIALISATION
Prof Marc Brown
MedPharm
THE FOURTH INDUSTRIAL REVOLUTION – ROBOTICS AND THE LABORATORY
Marc Brown and Jon Lenn look at MedPharm’s implementation of automated robotic systems in enhancing workflow and the company’s plans for the future implementation of robotics in formulation development.
EARLY INSIGHT
Mr Richard Joye
SERITECH LEVERAGES FAST-DETACHING, DISSOLVING MICRONEEDLE FOR TRANSDERMAL DRUG DELIVERY
Richard Joye and Tim Morch discuss the advantages of using dissolvable microneedles for the delivery of vaccines, particularly in regards to storage and transport, and introduce SeriTech’s fast-detaching dissolvable microneedle technology.
MICRONEEDLES
Dr Sebastian Braun
LTS
WHY THE CONSISTENT CHALLENGES SURROUNDING MAPS ARE DISSOLVING FAST
Sebastian Braun discusses the current state of microneedle-based transdermal drug delivery, covering available microneedle delivery methods, the US FDA’s current stance on microneedle technologies and LTS’s microarray patch (MAP) system and the possibilities it represents.
MICRONEEDLES
Dr John Vasilakos
Kindeva
MICRONEEDLES FOR INTRADERMAL DELIVERY OF CANCER VACCINES
John Vasilakos discusses the immuno-oncology market. He examines the role of cancer vaccines in supplementing other immuno-oncology therapies, as well as the value of delivering cancer vaccines intradermally.
SKIN
Dr Stefan Hellbardt
Aptar Pharma
AIRLESS DRUG DELIVERY: WIDELY ACCEPTED, ACCESSIBLE AND AVAILABLE
Stefan Hellbardt reflects on the role of Airless technology in the dermal drug delivery market and the benefits it offers.
SKIN
Audrey Chandra
Nemera
ENSURING FORMULATION PROTECTION AND PATIENT CARE WITH AIRLESS DISPENSERS
Audrey Chandra, Manuela Basso and Raphaële Audibert consider Nemera’s holistic approach to dermal drug delivery, explaining why airless technology is important for dermal pharmaceutical applications
EARLY INSIGHT
Dr Nicky Bertollo
Pharma Latch
AN ANGLED MICRONEEDLE PATCH FOR ENHANCED DRUG AND VACCINE DELIVERY
Nicky Bertollo, Ronan Byrne and Andrew Muddle introduce Pharma Latch – a user-centric angled microneedle patch technology. They discuss its key benefits, such as dramatically increased payload potential, precision, low cost and variable patch-wear times, and highlight how Pharma Latch has the potential to overcome many of the limitations of existing routes of administration for therapeutics and vaccines.
TRANSDERMAL
Jensen Lee
PRODUCT SHOWCASE: Logan Instruments’ Transdermal Testing Portfolio
Logan Instruments, a provider of laboratory instrumentation to the global pharmaceutical and cosmetics industries, with a focus on physical, dissolution and transdermal testing systems, showcases its pioneering transdermal testing system offering.
EARLY INSIGHT
Dr Eduardo Jorgensen
MEDICSEN: NEEDLE-FREE SMARTPATCH FOR PAINLESS DRUG DELIVERY
Eduardo W Jørgensen, Juan César de Mercado and José Carlos Montesinos describe the Smartpatch, a novel technology for subcutaneous delivery of drugs via a comfortable, pain-free patch using sonophoresis, based on Medicsen’s patented miniaturised ultrasound technology.
INDUSTRIALISATION
Prof Marc Brown
MedPharm
INNOVATION AND AUTOMATION IN TOPICAL FORMULATION DEVELOPMENT
Marc Brown, Jon Lenn and Charles Evans discuss the challenges faced by the pharmaceutical industry during the development of topical delivery formulations, and how MedPharm’s performance testing models help identify and mitigate risks during the process.
INTERVIEW
Aaron Mann
INTERVIEW WITH AARON MANN, CHIEF EXECUTIVE OFFICER, KINDEVA
In this exclusive interview with ONdrugDelivery, Aaron Mann discusses how Kindeva is positioned to move forward as a major CDMO specialising in inhalation and transdermal dosage forms, having been formed from 3M’s drug delivery in May 2020. We also cover the impact of Covid-19, environmental sustainability, and current challenges faced by the pharmaceutical industry.
ROUNDTABLE
Dr Jeremy Drummond
ROUNDTABLE: JEREMY DRUMMOND, MEDPHARM; STEPHEN RODE, LONZA; AND TORKEL GREN, RECIPHARM
In this roundtable discussion, Jeremy Drummond, Stephen Rode and Torkel Gren discuss trends with different drug dosage forms for different routes of administration, the rise of patient centricity including the shift from the blockbuster model to more tailored products.
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