Hovione

Hovione has an extensive CDMO offering, off-patent API capabilities, a proprietary product pipeline and associated supporting services and capabilities. Inhalation is a notable area of focus for Hovione. It has developed its own DPIs, and offers inhalation product development services.

Associated Companies

Hovione Technology Ltd

Head Office
Hovione
Sete Casas
2674 – 506 Loures
Portugal

Phone / Contact

T: +351 21 982 9000
F: +351 21 982 9368

Articles by Hovione

Dr Susana Saldanha

HIGH-DOSE DELIVERY PLATFORM FOR CRYSTALLINE DPIs

Susana Saldanha, Lídia Santos and Rui Churro, discuss the benefits of crystalline formulations for inhalation devices.

CAPSULE FILLING FOR DPIs – LINKING PROCESS SCALES THROUGH ADVANCED CHARACTERISATION AND QUALITY BY DESIGN

Rui Churro, Carolina Lopes and João Pires discuss the value of rheological characterisation of powders to expedite and de-risk the scale-up of DPI capsule-filling processes.

SEMI-AUTOMATION IN INHALER TESTING – EXPLORING THE POTENTIAL AND PRACTICALITIES

João Pereira, Raquel Borda D’Água, Mark Copley and Anna Sipitanou, discuss the semi-automation of cascade impactor testing and the benefits it can bring in terms of quality of orally inhaled product test data, and reductions in cost and effort associated with routine, critical measurements.

INTEGRATED DESIGN SPACE TO DEVELOP BETTER DPI FORMULATIONS

Filipa Maia and Maria Palha report a study whose objective was to establish relationships between blend rheology, product performance and capsule filling process efficiency.

Dr Eunice Costa

DESIGN OF COMPOSITE PARTICLES VIA SPRAY DRYING FOR DPI FORMULATIONS

Eunice Costa, Filipe Neves and Cláudia Moura describe how composite formulations - API embedded in an excipient matrix - overcome the challenges in inhalation powder development.

Dr Eunice Costa

SCALE-UP & QBD APPROACHES FOR SPRAY-DRIED INHALATION FORMULATIONS

Eunice Costa, Filipe Neves, Gonçalo Andrade and Conrad Winters describe the strong position of inhalable products in preclinical and clinical pipelines and make the case for formulation-based approaches to enable and enhance pulmonary product development. Spray-drying technology in particular is highlighted as a highly favourable, scalable manufacturing technique for inhalable composite particles.

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